FELIPE ANTUNES SANTOS
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Resumo IPEN-doc 23562 Vidros biocidas baseados no sistema Nb2O5-SiO-CAO-Na2O2016 - SILVA, A.C.; MELLO-CASTANHO, S.R.; SANTOS, F.A.; SANTOS, C.Neste trabalho, foram desenvolvidos vidros com base no sistema de SiO-CaO-Na2O contendo diferentes teores de Nb2O5. Estes vidros foram fundidos a 1500°C por 4 horas seguido de “quenching” em molde metálico e recozimento a 500°C por duas horas e resfriamento natural no forno. Corpos de prova de aço inoxidável 316L e ligas de titânio foram recobertas com os materiais Os ensaios de caracterização utilizaram as técnicas de DRX, FT-IR e análise da expansão térmica. Também realizou-se ensaios de citotoxicidade utilizando a metodologia de absorção de vermelho neutro onde foi indicado o crescimento celular normal, o que permite a sua utilização como biomaterial. A atividade biocida foi avaliada através da incubação de vidro em suspensão bacteriana (E.coli) a 37°C sob agitação. A composição com alto teor de de SiO2 e baixo teor de Nb2O5 apresentou maior atividade biocida e o coeficiente de expansão térmica indicam compatibilidade dos materiais térmica com o aço inoxidável 316L e ligas de titânio.Resumo IPEN-doc 23563 Coating glass-ceramics bioactive based on Nb2O5-SiOCaO- Na2O system2016 - MELLO-CASTANHO, SONIA; SANTOS, FELIPE; BARTOLOME, JOSE; SILVA, ANTONIOThe request for biomaterials which interact and provide proper feedback to bodily environment is increasing and so, the need for alternative materials development, from the process or biological feedback points of view, is a necessity. In this context, glass and glassceramic are interesting alternatives due to their chemical and structural characteristics possibilities. The surface coating of a specific implant with bioglass associated to biocide activity can lead to a significant impact on patient life quality, reducing risks associated to prostheses replacement due to infections, which is currently one of the most concerning and important factors in implantology. In this work, glassceramic materials based on SiO-CaO-Na2O system containing different percentages of Nb2O5 were developed. Glasses were melted at 1500°C and thermally treated at 750°C-2h. The materials were characterized by X-Ray Diffraction (XRD), to analyses indicated partial crystallization of glassy matrix. The Fourier Transform Infrared (FTIR) Spectroscopy and Dilatometry also were used to structural and thermal behavior analyses respectively. Citotoxicity tests were performed using neutral red uptake methodology and indicated normal cell growth, which enables the use as biomaterial. Biocide activity was evaluated through glass-ceramic incubation in bacterial suspension (Escherichia coli) at 37°C under shaking. A composition with higher contents of SiO2 and Nb2O5 presented higher biocide activity and coefficient of thermal expansion (CTE) evaluated indicate thermal connection with stainless steel 316L and titanium alloys.Artigo IPEN-doc 22656 Biocide glass based on Nb2O5-SiO-CaO-Na2O system2016 - SANTOS, FELIPE A.; SILVA, ANTONIO C.; SANTOS, CLAUDINEI; SIMBA, BRUNO G.; BARTOLOME, JOSE F.; DURAN, TERESA; FERNANDEZ-GARCIA, ELISA; ROGERO, SIZUE O.; MELLO-CASTANHO, SONIA R.H.In this work,glasses based on SiO-CaO-Na2O system containing different Nb2O5 contents were developed. Glasses were melted at 1500 °C and quenched in a metallic mould. Citotoxicity tests were performed using neutral red uptake methodology and indicated normal cell growth, which enables the use as biomaterial. Biocide activity was evaluated through glass incubation in bacterial suspension (Escherichia coli) at 37 °C under shaking. The composition with higher content of SiO2 and lower content of Nb2O5 presented higher biocide activity and the coefficient of thermal expansion indicate thermal compatibility with stainless steel 316L and titanium alloys.