PAULO FLAVIO DE MACEDO GOUVEA
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Capítulo IPEN-doc 28722 Caracterização química de argilas de uso terapêutico e cosmético2022 - TORRECILHA, JEFFERSON K.; GOUVEA, PAULO F. de M.; SOUFIA, LAYLA B.; MARTINS, JOAO P.M.; SILVA, PAULO S.C. daO uso de argilas com finalidade medicinal e cosmética é milenar e no Brasil, poucos estudos são feitos referentes a caracterização elementar deste material. Este trabalho teve como objetivo mostrar as pesquisas realizadas no IPEN com o uso do reator IEA-R1 para caracterizar argilas de uso medicinal e cosmético avaliando sua composição, composição da matéria orgânica agregada e disponibilidade de seus elementos constituintes. Também foi realizado um estudo sobre a produção de peloide produzido artificialmente com águas minero-medicinais e do mar. Com os resultados obtidos foi possível concluir que a técnica de análise por ativação neutrônica é muito eficaz e permite resultados confiáveis sobre o material estudado.Artigo IPEN-doc 27789 Evaluation of the use of sterilized and non-sterilized Peruibe Black Mud in patients with knee osteoarthritis2021 - GOUVEA, PAULO F.M.; BRITSCHKA, ZELIA M.N.; GOMES, CRISTINA de O.M.S.; QUEIROZ, NICOLLE G.T. de; SALVADOR, PABLO A.V.; SILVA, PAULO S.C.This study aimed to evaluate the effects of treatment with Peruíbe Black Mud (PBM) on the clinical parameters and quality of life of patients with knee osteoarthritis and to compare the effects of PBM samples simply matured in seawater and PBM sterilized by gamma radiation. A controlled, double-blind trial was conducted with 41 patients divided into two treatment groups composed of 20 and 21 patients: one group was treated with matured PBM and the other with sterilized PBM. Evaluations were done using theWestern Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the Medical Outcomes Study Short Form 36 (SF-36) questionnaires, the Kellgren and Lawrence (KL) radiographic scale, and the quantification of the serum levels of inflammatory biomarkers. An improvement in pain, physical functions, and quality of life was observed in all of the patients who underwent treatment with both simply matured and sterilized PBM. Nine patients showed remission in the KL radiographic scale, but no statistically significant differences were observed in the serum levels of inflammatory mediators before or after treatment. Peruíbe Black Mud proves to be a useful tool as an adjuvant treatment for knee osteoarthritis (OA), as shown by the results of the WOMAC and SF-36 questionnaires and by the remission of the radiographic grade of some patients on the Kellgren and Lawrence scale.Artigo IPEN-doc 26228 Radiological characterization of peloids maturated with Águas de Lindóia, Poços de Caldas and Peruíbe waters2019 - TORRECILHA, JEFFERSON K.; MARRICHI, JUSSARA M.O.; SOUZA, EDUARDO A.P.; GOUVEA, PAULO F. de M.; SILVA, PAULO S.C..One of the concerns about using mineral clay for therapy treatments is its radioactivity content due to natural radionuclides, normally, associated with the clays. This work proposes to characterize the natural radionuclides of the peloids obtained by the maturation process of mixing bentonite and montmorillonite with different mineral medicinal waters from Águas de Lindóia (SP), Peruíbe (SP) and Poços de Caldas (MG). For this procedure, gray end green bentonite samples were left in contact with running water for three, six and nine months, after this, they were collected, dried, transferred to a mortar, crushed and placed in approximately 40 cm3 polyethylene flasks, sealed and set apart for about four weeks, prior to the measurements. The concentration of 210Pb was determined by measuring the activity of its low energy peak (47 keV). Comparing the gray and green bentonite peloids, all the activity concentration of radionuclides are higher in gray ones, except 40K. The activity concentration varied from 84 to 156 Bq kg−1 (228Ra), 25 to 156 Bq kg−1 (228Th), 9 to 161 Bq kg−1 (226Ra), 39 to 256 Bq kg−1 (210Pb) and 162 to 1070 Bq kg−1 (40K).Artigo IPEN-doc 21214 Chemical and radiological characterization of Peruibe black mud2015 - SILVA, PAULO S.C. da; TORRECILHA, JEFFERSON K.; GOUVEA, PAULO F. de M.; MADUAR, MARCELO F.; OLIVEIRA, SONIA M.B. de; SCAPIN, MARCOS A.