DALTON GIOVANNI NOGUEIRA DA SILVA

DALTON GIOVANNI NOGUEIRA DA SILVA

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X- ray experimental set-up for in-vitro nail test
2023 - ZAMBONI, C.B.; GIOVANNI, D.N.S.; ALMEIDA, M.R.; TODO, A.S.; SABARA, F.; RODRIGUES JUNIOR, O.
In this investigation, the elements Ca and S were evaluated in a single nail clipping using compact and portable X-ray spectrometer model X-123 SDD with Ag target. Experimental conditions for current, voltage and excitation time were investigated. These analyses can be useful for a variety of applications, including nutritional and medical diagnosis, such as, the evaluation of bone dysfunctions by measurement of Ca (bone decalcification) and S for nutrition evaluations (collagen production). This analysis offers some benefits comparatively to blood and serum analyses, such as, non-invasive collection, fast analyses (minutes) and low cost. In addition, nail clippings are simple to obtain, easy to store, and easy to transport. This pilot study show a positive expectation for clinical application using in-vitro nail test.
Comparação de desempenho do espectrômetro portátil de fluorescência de raios-X utilizando alvos de Au e Ag para análise de amostras na área da saúde
2022 - TASSO, ORION G.; ZAMBONI, CIBELE B.; SILVA, ANA C.K. de S.; MEDEIROS, JOSE A.G. de; SILVA, DALTON G.N. da
Este trabalho teve por objetivo avaliar o desempenho do espectrômetro portátil e compacto de Fluorescência de Raios-X (pFRX), para dosagem de íons em amostras biológicas de interesse na área da saúde (prioritariamente fluidos corpóreos como soro e urina), utilizando alvos de Prata (Ag) e Ouro (Au). O foco das comparações foi direcionado às análises quantitativas de elementos de relevância clínica e nutricional (prioritariamente a dosagem de Ca, Cl, Fe, K, P e S). Para este estudo foram avaliados (para cada alvo) os parâmetros: linearidade, reprodutibilidade, acurácia, sensibilidade e limite de detecção. Essas investigações permitiram a realização de um estudo comparativo entre os alvos, com a finalidade de fornecer subsídios que permitem a escolha adequada do alvo (Ag e/ou Au), agilizando as medidas além de fornecer resultados mais precisos. Os resultados de FRX em soro e urina formam comparados com as dosagens obtidas pela técnica de Análise por Ativação com Nêutrons e apresentaram boa concordância.
Quantitative analysis of light elements using compact XRF spectrometers
2021 - ZAMBONI, CIBELE B.; SILVA, DALTON G.N. da; TASSO, ORION G.; MEDEIROS, JOSE A.G. de; AZEVEDO, MARIA R.A. de
The performance of two compact X-Ray Fluorescence (FRX) spectrometers consisting of Ag and Au X-ray mini-tubes associated with a Si Drift detector was checked for clinical finality. Using the Energy Dispersive X-Ray Fluorescence technique (FRXDE) specific light elements of clinical relevance (Ca, Cl, K and Fe) were determined in human whole blood samples without chemical digestion using direct and non-destructive analysis, in air atmosphere. A comparative study between Ag and Au targets data was carried out and the results are in good agreement.
Evaluation of iron in blood of athletes by the EDXRF technique
2019 - ALMEIDA, MATEUS R. de; ZAMBONI, CIBELE B.; SILVA, DALTON G.N. da; AZEVEDO, MARIA R.
The aim of this study was evaluate Fe in blood of athletes from different modalities (judo athletes, cyclist and long distance runners) by X-ray Fluorescence methodology using portable equipment, as an alternative for clinical practice. The study showed the practicality and efficacy of using this methodology for successive clinical evaluations, during the preparation period of competitions, providing data that help in the elaboration of a balanced diet, as well as contribute to the proposal of new clinical evaluation protocols. In addition, the results emphasize the need to adopt differentiated diets for adequate iron intake as a function of sports activity.