MARCOS SOBRAL RIBEIRO

MARCOS SOBRAL RIBEIRO

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Laser em baixa intensidade
2004 - RIBEIRO, M.S.; ZEZELL, D.M.
Prevention of bloodstream infections by photodynamic inactivation of multi-resistant Pseudomonas aeruginosa in burn wounds
2010 - HASHIMOTO, M.C.E.; PRATES, R.A.; TOFFOLI, D.J.; COURROL, L.C.; RIBEIRO, M.S.
Modelo de estudo in vitro da distribuição da luz em infecções de biofilme de Candida albicans
2012 - NUNEZ, S.C.; SABINO, C.P.; GARCEZ, A.S.; RIBEIRO, M.S.
Desenvolvimento de um modelo in vivo para o estudo do efeito fotodinâmico em infecção fúngica
2012 - RIBEIRO, M.S.; KATO, I.T.; SABINO, C.P.; SANTOS, C.C.; PRATES, R.A.
Photodynamic inactivation of antibiotic resistant strain of Pseudomonas aeruginosa in vivo
2009 - HASHIMOTO, M.C.E.; TOFFOLI, D.J.; PRATES, R.A.; COURROL, LILIA C.; RIBEIRO, M.S.
Burns are frequently contamined by pathogenic microorganisms and the widespread occurrence of antibiotic resistant strains of Pseudomonas aeruginosa in hospitals is a matter of growing concern. Hypocrellin B (HB) is a new generation photosensitizer extracted from the fungus Hypocrella bambusae with absorption bands at 460, 546 and 584 nm. Lanthanide ions change the HB molecular structure and a red shift in the absorption band is observed as well as an increase in the singlet oxygen quantum yield. In this study, we report the use of HB:La+3 to kill resistant strain of P. aeruginosa infected burns. Burns were produced on the back of mice and wounds were infected subcutaneously with 1x109 cfu/mL of P. aeruginosa. Three-hours after inoculation, the animals were divided into 4 groups: control, HB:La+3, blue LED and HB:La+3+blue LED. PDT was performed using 10µM HB:La+3 and 500mW light-emitting diode (LED) emitting at λ=470nm±20nm during 120s. The animals of all groups were killed and the infected skin was removed for bacterial counting. Mice with photosensitizer alone, light alone or untreated infected wounds presented 1x108 cfu/g while mice PDT-treated showed a reduction of 2 logs compared to untreated control. These results suggest that HB:La+3 associated to blue LED is effective in diminishing antibiotic resistant strain P. aeruginosa in infected burns.
Histological study of wound healing in rats following He-Ne and GaAlAs laser radiation
1998 - RIBEIRO, M.S.; ZEZELL, D.M.; MALDONADO, E.P.; VIEIRA JUNIOR, N.D.; CARBONE, K.; PELLEGRINI, C.M.R.; ZORN, T.M.T.
Incorporation of [sup(3)H]-proline in the dermis of mice following He-Ne polarized laser radiation in the wound healing process. A preliminary study
1998 - RIBEIRO, M.S.; ZEZELL, D.M.; FONTENELE, J.D.; PELLEGRINI, C.M.R.; ZORN, T.M.T.
Photodynamic antimicrobial therapy associated with surgical endodontic treatment
2011 - GARCEZ, A.S.; NUNEZ, S.C.; FREGNANI, E.; SELLERA, D.P.; RIBEIRO, M.S.; SUZUKI, H.
É realmente necessário o uso de fibra óptica na PDT endodôntica?
2011 - RODRIGUEZ, H.M.H.; GARCEZ, A.S.; DAGHASTANLI, N.A.; NUNEZ, S.C.; FREGNANI, E.R.; AZAMBUJA JUNIOR, N.; SABINO, C.P.; RIBEIRO, M.S.
Efeito da terapia fotodinâmica na matriz extracelular de bactériaGram negativa avaliado por microscopia de força atômica
2010 - GARCEZ, A.S.; NUNEZ, S.C.; RIBEIRO, M.S.; MIYAKAWA, W.