60Co irradiation effects in Gd2O3 and Er2O3 nanoparticles
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2017
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INTERNATIONAL TOPICAL MEETING ON INDUSTRIAL RADIATION AND RADIOISOTOPE MEASUREMENT APPLICATIONS, 10th
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Resumo
Enhanced radiosensitization in tissues using high-Z materials has been observed since
80’s, and the application of nanoparticles (NPs) for this purpose has been widely studied in the past years. NPs use in radiotherapy procedures implies to submit them to
high dose radiation beams which might cause damage to these particles resulting in the
release of toxic material to the biological environment. In order to verify radiation effect
in Gd2O3 and Er2O3 NPs doses from 3 Gy to 20 Gy produced by a 60Co source were
tested. The study with X-ray diffraction (XRD) showed, for Gd2O3-NP samples, a
change in peaks positions featuring a decrease in the lattice parameter as function of
dose increase up to 5 Gy. From this point lattice parameter presented no significant
change. For Er2O3-NP the lattice parameters do not present a behavior in function of
dose. A peak change can be noticed for samples irradiated with 5 Gy and 20 Gy, and
samples irradiated with 3 Gy, 7 Gy and no irradiated presented no significant peak
displacement. Perturbed angular correlation (PAC) gamma-gamma spectroscopy was
performed using 111In(111Cd) as probe nuclei. Despite non-symmetric site C
parameters presented no substantial change results showed a slight variation of eta
parameter for the symmetric site D for both samples, which may indicate a distortion at
that site caused by the radiation. This study showed that radiation doses used in
radiotherapy procedures may cause damage to nanoparticles structures. However, this
damage is not great enough to break the nanoparticle and liberate toxic Gd3+ or Er3+
into patient organism.
Como referenciar
CORREA, E.L.; BOSCH-SANTOS, B.; PEREIRA, L.F.D.; CARBONARI, A.W.; POTIENS, M.P.A. 60Co irradiation effects in Gd2O3 and Er2O3 nanoparticles. In: INTERNATIONAL TOPICAL MEETING ON INDUSTRIAL RADIATION AND RADIOISOTOPE MEASUREMENT APPLICATIONS, 10th, July 09-13, 2017, Chicago, IL, USA. Abstract... p. 13-14. Disponível em: http://repositorio.ipen.br/handle/123456789/27948. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.