Development and cytotoxicity evaluation of SiAlONs ceramics
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Materials Science and Engineering, C
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SiAlONs are ceramics with high potential as biomaterials due to their chemical stability, associated with suitable mechanical properties, such as
high fracture toughness and fracture resistance. The objective of this work was to investigate the mechanical properties and the cytotoxicity of these
ceramic materials. Three different compositions were prepared, using silicon nitride, aluminum nitride and a rare earth oxide mixture as starting
powders, yielding Si3N4–SiAlON composites or pure SiAlON ceramics, after hot-pressing at 1750 °C, for 30 min. The sintered samples were
characterized by X-ray diffraction analysis (XRD) and scanning electron microscopy (SEM). Furthermore, hardness and fracture toughness were
determined using the Vicker's indentation method. The biological compatibility was evaluated by in vitro cytotoxicity tests. Ceramic with elevated
hardness, ranging between 17 and 21 GPa, and high fracture toughness of 5 to 6 MPa m1/2 were obtained. Since a nontoxic behavior was observed in
the cytotoxicity tests, it may be assumed that SiAlON-based ceramics are viable materials for clinical applications.
Como referenciar
SANTOS, C.; RIBEIRO, S.; DAGUANO, J.K.M.F.; ROGERO, S.O.; STRECKER, K.; SILVA, C.R.M. Development and cytotoxicity evaluation of SiAlONs ceramics. Materials Science and Engineering, C, v. 27, p. 148-153, 2007. DOI: 10.1016/j.msec.2006.04.003. Disponível em: http://repositorio.ipen.br/handle/123456789/5209. Acesso em: 20 Mar 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.