An updated review of macro, micro, and nanostructured hydrogels for biomedical and pharmaceutical applications

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dc.contributor.authorLIMA, CAROLINE S.A. dept_BR
dc.contributor.authorBALOGH, TATIANA S.pt_BR
dc.contributor.authorVARCA, JUSTINE P.R.O.pt_BR
dc.contributor.authorVARCA, GUSTAVO H.C.pt_BR
dc.contributor.authorLUGAO, ADEMAR B.pt_BR
dc.contributor.authorCAMACHO-CRUZ, LUIS A.pt_BR
dc.contributor.authorBUCIO, EMILIOpt_BR
dc.contributor.authorKADLUBOWSKI, SLAWOMIR S.pt_BR
dc.coverageInternacionalpt_BR
dc.date.accessioned2021-02-24T13:29:40Z
dc.date.available2021-02-24T13:29:40Z
dc.date.issued2020pt_BR
dc.description.abstractHydrogels are materials with wide applications in several fields, including the biomedical and pharmaceutical industries. Their properties such as the capacity of absorbing great amounts of aqueous solutions without losing shape and mechanical properties, as well as loading drugs of different nature, including hydrophobic ones and biomolecules, give an idea of their versatility and promising demand. As they have been explored in a great number of studies for years, many routes of synthesis have been developed, especially for chemical/permanent hydrogels. In the same way, stimuli-responsive hydrogels, also known as intelligent materials, have been explored too, enhancing the regulation of properties such as targeting and drug release. By controlling the particle size, hydrogel on the micro- and nanoscale have been studied likewise and have increased, even more, the possibilities for applications of the so-called XXI century materials. In this paper, we aimed to produce an overview of the recent studies concerning methods of synthesis, biomedical, and pharmaceutical applications of macro-, micro, and nanogels.pt_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorshipInternational Atomic Energy Agency (IAEA)pt_BR
dc.description.sponsorshipSistema Nacional de Laboratórios em Nanotecnologias (SisNANO)pt_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorshipIDCNPq: 402887/2013-1pt_BR
dc.description.sponsorshipIDIAEA: CRP F22064pt_BR
dc.description.sponsorshipIDSisNano: 442527/2019-5pt_BR
dc.description.sponsorshipIDFAPESP: 19/01315-1; 15/13979-0pt_BR
dc.format.extent1-28pt_BR
dc.identifier.citationLIMA, CAROLINE S.A. de; BALOGH, TATIANA S.; VARCA, JUSTINE P.R.O.; VARCA, GUSTAVO H.C.; LUGAO, ADEMAR B.; CAMACHO-CRUZ, LUIS A.; BUCIO, EMILIO; KADLUBOWSKI, SLAWOMIR S. An updated review of macro, micro, and nanostructured hydrogels for biomedical and pharmaceutical applications. <b>Pharmaceutics</b>, v. 12, n. 10, p. 1-28, 2020. DOI: <a href="https://dx.doi.org/10.3390/pharmaceutics12100970">10.3390/pharmaceutics12100970</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/31809.
dc.identifier.doi10.3390/pharmaceutics12100970pt_BR
dc.identifier.fasciculo10pt_BR
dc.identifier.issn1999-4923pt_BR
dc.identifier.orcid0000-0002-1737-3191pt_BR
dc.identifier.orcid0000-0002-6545-237Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1737-3191
dc.identifier.percentilfi89.64pt_BR
dc.identifier.percentilfiCiteScore68.00
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/31809
dc.identifier.vol12pt_BR
dc.relation.ispartofPharmaceuticspt_BR
dc.rightsopenAccesspt_BR
dc.subjecthydrogels
dc.subjectdrugs
dc.subjectsynthesis
dc.subjectcross-linking
dc.subjectskin
dc.subjectanimal tissues
dc.subjectgamma radiation
dc.titleAn updated review of macro, micro, and nanostructured hydrogels for biomedical and pharmaceutical applicationspt_BR
dc.typeArtigo de periódicopt_BR
dspace.entity.typePublication
ipen.autorTATIANA SANTANA BALOGH
ipen.autorADEMAR BENEVOLO LUGAO
ipen.autorGUSTAVO HENRIQUE COSTAVARCA
ipen.autorJUSTINE PAULA RAMOS DE OLIVEIRA
ipen.autorCAROLINE SANTOS ALVES DE LIMA
ipen.codigoautor14431
ipen.codigoautor339
ipen.codigoautor8661
ipen.codigoautor8726
ipen.codigoautor14945
ipen.contributor.ipenauthorTATIANA SANTANA BALOGH
ipen.contributor.ipenauthorADEMAR BENEVOLO LUGAO
ipen.contributor.ipenauthorGUSTAVO HENRIQUE COSTAVARCA
ipen.contributor.ipenauthorJUSTINE PAULA RAMOS DE OLIVEIRA
ipen.contributor.ipenauthorCAROLINE SANTOS ALVES DE LIMA
ipen.date.recebimento21-02
ipen.identifier.fi6.321pt_BR
ipen.identifier.fiCiteScore4.7
ipen.identifier.ipendoc27582pt_BR
ipen.identifier.iwosWoSpt_BR
ipen.range.fi6.000 ou mais
ipen.range.percentilfi75.00 - 100.00
ipen.type.genreArtigo
relation.isAuthorOfPublicationb1f1c387-fb7b-4445-93d5-678576c4aa8d
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relation.isAuthorOfPublication00496d62-f664-40ae-bf64-e0db91a39f77
relation.isAuthorOfPublication.latestForDiscovery00496d62-f664-40ae-bf64-e0db91a39f77
sigepi.autor.atividadeLUGAO, ADEMAR B.:339:740:Npt_BR
sigepi.autor.atividadeVARCA, GUSTAVO H.C.:8661:740:Npt_BR
sigepi.autor.atividadeVARCA, JUSTINE P.R.O.:8726:740:Npt_BR
sigepi.autor.atividadeBALOGH, TATIANA S.:14431:740:Npt_BR
sigepi.autor.atividadeLIMA, CAROLINE S.A. de:14945:740:Spt_BR
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