Label-free Infrared spectroscopic imaging for characterization of necrotic tissue areas on cutaneous squamous cell carcinoma

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dc.contributor.authorLIMA, CASSIO A.pt_BR
dc.contributor.authorCORREA, LUCIANApt_BR
dc.contributor.authorBYRNE, HUGH J.pt_BR
dc.contributor.authorZEZELL, DENISE M.pt_BR
dc.contributor.editorMAHADEVAN-JANSEN, ANITApt_BR
dc.contributor.editorGRUNDFEST, WARREN S.pt_BR
dc.coverageInternacionalpt_BR
dc.creator.eventoSPIE PHOTONICS WEST; SPIE BIOSpt_BR
dc.date.accessioned2019-09-02T12:58:14Z
dc.date.available2019-09-02T12:58:14Z
dc.date.eventoFebruary 2-7, 2019pt_BR
dc.description.abstractIn this study, FTIR spectroscopy was used to evaluate the overall biochemical status of necrotic tissue areas of cutaneous squamous cell carcinoma chemically-induced on mice. FTIR hyperspectral image collected from specimen showed high correlation with the photomicrograph obtained by light microscopy, in which we were able to identify clusters associated to keratin, necrosis and regions with no tissue. Alterations in the protein content were documented in the necrotic tissue areas, indicating changes on protein conformation.pt_BR
dc.format.extent1086812-1 - 1086812-6pt_BR
dc.identifier.citationLIMA, CASSIO A.; CORREA, LUCIANA; BYRNE, HUGH J.; ZEZELL, DENISE M. Label-free Infrared spectroscopic imaging for characterization of necrotic tissue areas on cutaneous squamous cell carcinoma. In: MAHADEVAN-JANSEN, ANITA (ed.); GRUNDFEST, WARREN S. (ed.). In: SPIE PHOTONICS WEST; SPIE BIOS, February 2-7, 2019, San Francisco, USA. <b>Proceedings...</b> Washington, USA: SPIE, 2019. p. 1086812-1 - 1086812-6. (Proceedings SPIE 10868, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVII). DOI: <a href="https://dx.doi.org/10.1117/12.2510711">10.1117/12.2510711</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/30150.
dc.identifier.doi10.1117/12.2510711pt_BR
dc.identifier.orcid0000-0001-7404-9606pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-7404-9606
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/30150
dc.localWashington, USApt_BR
dc.local.eventoSan Francisco, USApt_BR
dc.publisherSPIEpt_BR
dc.relation.ispartofseriesProceedings SPIE 10868, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XVIIpt_BR
dc.rightsclosedAccesspt_BR
dc.subjectfourier transformation
dc.subjectinfrared spectra
dc.subjectskin
dc.subjectcarcinomas
dc.subjectnecrosis
dc.subjectcarcinogenesis
dc.subjecthistology
dc.subjectanimal tissues
dc.titleLabel-free Infrared spectroscopic imaging for characterization of necrotic tissue areas on cutaneous squamous cell carcinomapt_BR
dc.typeTexto completo de eventopt_BR
dspace.entity.typePublication
ipen.autorDENISE MARIA ZEZELL
ipen.autorCASSIO APARECIDO LIMA
ipen.codigoautor693
ipen.codigoautor11396
ipen.contributor.ipenauthorDENISE MARIA ZEZELL
ipen.contributor.ipenauthorCASSIO APARECIDO LIMA
ipen.date.recebimento19-09
ipen.event.datapadronizada2019pt_BR
ipen.identifier.ipendoc25944pt_BR
ipen.identifier.ods3
ipen.notas.internasProceedingspt_BR
ipen.type.genreArtigo
relation.isAuthorOfPublicationa565f8ad-3432-4891-98c0-a587f497db21
relation.isAuthorOfPublication72af3b0f-7d99-44eb-a234-9027c26dc589
relation.isAuthorOfPublication.latestForDiscovery72af3b0f-7d99-44eb-a234-9027c26dc589
sigepi.autor.atividadeZEZELL, DENISE M.:693:920:Npt_BR
sigepi.autor.atividadeLIMA, CASSIO A.:11396:920:Spt_BR

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