Analyses of inorganic elements in saliva from Amblyomma cajennense specie from Brasil
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2008
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REUNIAO DE TRABALHO SOBRE FISICA NUCLEAR NO BRASIL, 31.
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Resumo
Neutron Activation Analysis technique (NAA) has been applied to determine some element
concentrations in saliva samples of tick Amblyomma cajennense specie aiming to identify
its elemental composition. The relevance of studying this biological material is related to its
medical application. Molecules biological with anticoagulant proprieties from its saliva
presents have been designed to target specific coagulation enzymes or steps in the
coagulation pathway.
The principle of this technique is the irradiation of the biological material with thermal
neutrons followed by the measurement of the γ-ray activities induced in the biological
sample where the elements activated can be identified by the nuclear properties of γ-rays.
The biological material came from Butantan Institute at São Paulo city, Brazil. For sample
preparation, about 0.5 ml of saliva were collect from Amblyomma cajennense specie and
sealed into an individual polyethylene bag and irradiated in the IEA-R1 nuclear reactor at
IPEN/SP (IEA-R1, 2-4MW, pool type), for few minutes. A γ- spectrometer system with a
semiconductor detector (HPGe) connected to an ADCAM multichannel analyzer were used
to measure the induced gamma-ray activity. Using this procedure it was possible to identify
the following radioactive nuclides: 80Br (T1/2=9 min, Eγ =3084 keV), 49Ca (T1/2=9 min, Eγ
=3084 keV), 38Cl (T1/2=37 min, Eγ =1642 keV), 42K (T1/2=12h, Eγ =1525 keV), 31P
(T1/2=2min, Eγ =1778 keV), 24Na (T1/2=15h, Eγ =1368 keV) and 37S (T1/2=5min, Eγ =3104
keV).
The concentration of each element was obtained by using the ATIVAÇÃO software. The
results were correlated with the indicative interval values for these elements in humans.
Como referenciar
MEDEIROS, I.M.M.A.; ZAMBONI, C.B.; OLIVEIRA, D.G.L.; CHUDZINSKI-TAVASSI, A.M. Analyses of inorganic elements in saliva from Amblyomma cajennense specie from Brasil. In: REUNIAO DE TRABALHO SOBRE FISICA NUCLEAR NO BRASIL, 31., 8-12 de setembro, 2008, Maresias, SP. Resumo... p. 26. Disponível em: http://repositorio.ipen.br/handle/123456789/22845. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.