Iron determination in whole blood samples of dystrophic mouse strains using X-Ray fluorescence spectrometry
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Journal of Musculoskeletal Disorders and Treatment
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Several diseases can be monitored by assessing the variation
of specific ion concentration in body fluids. This study
proposes an alternative analysis, based on the X-ray fluorescence
spectrometry technique, for the investigation of
iron (Fe concentration determination) in whole blood of the
dystrophic animal models. We performed blood analyses
from three different strains with Muscular Dystrophy (Dmdmdx/
J, SJL/J and A/J) and from healthy (C57BL/6J) mice strain
adopted as the control group. The results emphasize that
iron levels in whole blood male samples of SJL/J and A/J
are significantly higher. Related to the gender for Dmdmdx/J
and SJL/J mouse strains the comparison emphasizes that
iron level increase for males. The study of Fe behavior in
whole blood mice samples with muscular dystrophy contributes
to its diagnosis, providing a better understanding of this
disease.
Como referenciar
METAIRON, SABRINA; ZAMBONI, CIBELE B.; GIOVANNI, DALTON N. da S.; SUZUKI, MIRIAM F.; BUENO JUNIOR, CARLOS R.; RIZZUTTO, MARCIA de A. Iron determination in whole blood samples of dystrophic mouse strains using X-Ray fluorescence spectrometry. Journal of Musculoskeletal Disorders and Treatment, v. 03, n. 02, p. 1-5, 2017. DOI: 10.23937/2572-3243.1510039. Disponível em: http://repositorio.ipen.br/handle/123456789/28519. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.