Applications of europium tetracycline complex: a review
Carregando...
Data
Data de publicação
Autores IPEN
Orientador
Título da Revista
ISSN da Revista
Título do Volume
É parte de
É parte de
É parte de
Current Pharmaceuticals analysis
Exportar
Resumo
Europium solutions present low absorption coefficients and, due to the energy transfer between europium ions
and the OH vibration of coordinated water molecules, there is a significant non-radiative relaxation and no emission is observed. However, when europium complexes with tetracycline (EuTc), it exhibits and intense and narrow emission band
centered on 615 nm, characteristic of the 5
D0 5
F2 transition within the lanthanide ion. The tetracycline molecule acts as
an “antenna” or sensitizer, absorbing the excitation light and transferring the energy to the lanthanide ion.
A major increase in the luminescence of the EuTc complex was observed in the presence of hydrogen peroxide and also
urea hydrogen peroxide. The possibility of quantifying the hydrogen peroxide using luminescence measurements is also
promising for the indirect quantification of glucose and cholesterol since enzymatic reactions generate hydrogen peroxide.
This principle can be applied to determine, indirectly, concentrations of lactose and galactose, alcohol, catalase, etc.
There are also other possibilities of EuTc applications: assay for phosphate, sensing and imaging of malate in aqueous solution, spectrofluorimetric determination of lecithin, heparin, human serum albumin, citrate and other intermediates in the
citric acid cycle, low density lipoproteins (LDL), the determination of the activity of phosphorylation, immunoassays, etc.
The purpose of this review is to describe and discuss the latest advances in analytical methodologies based in the luminescence properties of EuTc probes.
Como referenciar
COURROL, LILIA C.; SAMAD, RICARDO E. Applications of europium tetracycline complex: a review. Current Pharmaceuticals analysis, v. 4, p. 238-248, 2008. Disponível em: http://repositorio.ipen.br/handle/123456789/26630. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.