Dependence of optical attenuation coefficient and mechanical tension of irradiated human cartilage measured by optical coherence tomography
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Cell Tissue Bank
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Resumo
As banked human tissues are not widely
available, the development of new non-destructive and
contactless techniques to evaluate the quality of allografts before distribution for transplantation is very
important. Also, tissues will be processed accordingly to
standard procedures and to minimize disease transmission most tissue banks will include a decontamination or
sterilization step such as ionizing radiation. In this work,
we present a new method to evaluate the internal
structure of frozen or glycerol-processed human cartilages, submitted to various dosis of irradiation, using the
total optical attenuation coefficient retrieved from
optical coherence tomography (OCT) images. Our results
show a close relationship between tensile properties
and the total optical attenuation coefficient of cartilages. Therefore, OCT associated with the total optical
attenuation coefficient open a new window to evaluate
quantitatively biological changes in processed tissues.
Como referenciar
MARTINHO JUNIOR, A.C.; FREITAS, A.Z.; RAELE, M.P.; SANTIN, S.P.; SOARES, F.A.N.; HERSON, M.R.; MATHOR, M.B. Dependence of optical attenuation coefficient and mechanical tension of irradiated human cartilage measured by optical coherence tomography. Cell Tissue Bank, v. 16, n. 1, p. 47-53, 2015. DOI: 10.1007/s10561-013-9413-x. Disponível em: http://repositorio.ipen.br/handle/123456789/25317. Acesso em: 20 Mar 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.