Prospective ultramorphological characterization of human hair by optical coherence tomography
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Skin Research and Technology
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Background/purpose: The continuous advancement in
cosmetic science has led to an increasing demand for the
development of non-invasive, reliable scientific techniques
directed toward claim substantiation, which is of utmost
relevance, to obtain data regarding the efficacy and safety
of cosmetic products.
Methods: In this work, we used the optical coherence
tomography (OCT) technique to produce in vitro transversal
section-images of human hair. We also compared the OCT
signal before and after chemical treatment with an 18% w/w
ammonium thioglycolate solution.
Results: The mean diameter of the medulla was 29 7 mm
and the hair diameter was 122 16 mm in our samples of
standard Afro-ethnic hair. A three-dimensional (3D) image
was constructed starting from 601 cross-sectional images
(slices). Each slice was taken in steps of 6.0 mm at eight
frames per second, and the entire 3D image was constructed in 60 s.
Conclusion: It was possible to identify, using the A-scan
protocol, the principal structures: the cuticle, cortex and
medulla. After chemical treatment, it was not possible to
identify the main structures of hair fiber due to index
matching promoted by deleterious action of the chemical
agent.
Como referenciar
VELASCO, MARIA V.R.; BABY, ANDRE R.; SARRUF, FERNANDA D.; KANEKO, TELMA M.; SAMAD, RICARDO E.; VIEIRA JUNIOR, NILSON D.; FREITAS, ANDERSON Z. de. Prospective ultramorphological characterization of human hair by optical coherence tomography. Skin Research and Technology, v. 15, n. 4, p. 440-443, 2009. DOI: 10.1111/j.1600-0846.2009.00386.x. Disponível em: http://repositorio.ipen.br/handle/123456789/4888. Acesso em: 30 Dec 2025.
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