Development of Lignin/PEO nanofibers by electrospinning technique for tissue engineering application

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dc.contributor.authorNOGUEIRA, K.M.pt_BR
dc.contributor.authorVARCA, J.O.pt_BR
dc.contributor.authorLIMA, C.S.pt_BR
dc.contributor.authorCRUZ, C.C. dapt_BR
dc.contributor.authorRIBEIRO, A.H.pt_BR
dc.contributor.authorFREITAS, L.F.pt_BR
dc.contributor.authorVARCA, G.H.pt_BR
dc.contributor.authorLUGAO, A.B.pt_BR
dc.coverageInternacionalpt_BR
dc.creator.eventoPAN-AMERICAN NANOTECHNOLOGY CONFERENCE, 2ndpt_BR
dc.date.accessioned2021-03-04T18:37:20Z
dc.date.available2021-03-04T18:37:20Z
dc.date.eventoMarch 4-7, 2020pt_BR
dc.description.abstractLignin is a renewable carbon source and has been widely explored in different areas over the last years, especially in biomaterials such as dressings and other biomedical devices due its natural origin and low cost. Its chemical structure confers interesting properties such as antioxidant capacity, UV protection, bactericidal action and appropriate adsorption. Poly (ethylene oxide) (PEO) is used in electrospinning to facilitate the formation polymer fibers. The electrospinning technique has been largely explored in the bioengineering area towards designing nanomaterial with minimum defect and high surface area. The present work aimed the development of a lignin/PEO nanofiber by electrospinning technique. In practical terms, lignin/PEO solution was prepared following two different methods. In the first approach, polymer stock solutions were prepared in alkaline water by stirring at 70 °C. In the second, the polymer powders were mixed and dissolved together in dimethylformamide (DMF) under stirring at 80 °C. By both methods, PEO/lignin solutions were prepared at 10, 20 e 30% (w,v) solid content, at the ratios 99/1 and 95/5. For electrospinning parameters, the distance between ejector and plate collector was set to 15-20 cm, voltage to 20 kV and injection flow to 1 mL/h, chamber temperature to 40 °C and 30%. Nanofiber morphology was assessed by scanning electron microscopy and optical coherence tomography. Apparent porosity was measured by classical Archimedes method. Due to higher DMF dielectric constant compared to water, results showed that nanofibers made using DMF presented smaller beats formation and smaller fiber diameter. Nanofibers with higher solid content presented more uniform fibers with larger diameter. Nanofibers with higher lignin concentration presented larger number of beats and higher fiber diameter. However, lignin improved the system porosity in all cases. Further mechanical and biological experiments will be done, nevertheless, the nanofiber developed is a promising material to be applied in tissue engineering.pt_BR
dc.event.siglaPANNANOpt_BR
dc.identifier.citationNOGUEIRA, K.M.; VARCA, J.O.; LIMA, C.S.; CRUZ, C.C. da; RIBEIRO, A.H.; FREITAS, L.F.; VARCA, G.H.; LUGAO, A.B. Development of Lignin/PEO nanofibers by electrospinning technique for tissue engineering application. In: PAN-AMERICAN NANOTECHNOLOGY CONFERENCE, 2nd, March 4-7, 2020, Águas de Lindoia, SP. <b>Abstract...</b> Disponível em: http://repositorio.ipen.br/handle/123456789/31871.
dc.identifier.orcid0000-0002-1737-3191pt_BR
dc.identifier.orcid0000-0002-6545-237Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1737-3191
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/31871
dc.local.eventoÁguas de Lindoia, SPpt_BR
dc.rightsopenAccesspt_BR
dc.titleDevelopment of Lignin/PEO nanofibers by electrospinning technique for tissue engineering applicationpt_BR
dc.typeResumo de eventos científicospt_BR
dspace.entity.typePublication
ipen.autorCAROLINE SANTOS ALVES DE LIMA
ipen.autorANA PAULA HONORATO RIBEIRO
ipen.autorADEMAR BENEVOLO LUGAO
ipen.autorGUSTAVO HENRIQUE COSTAVARCA
ipen.autorLUCAS FREITAS DE FREITAS
ipen.autorCASSIA PRISCILA CUNHA DA CRUZ
ipen.autorJUSTINE PAULA RAMOS DE OLIVEIRA
ipen.autorKAMILA MOREIRA NOGUEIRA
ipen.codigoautor14945
ipen.codigoautor15059
ipen.codigoautor339
ipen.codigoautor8661
ipen.codigoautor14818
ipen.codigoautor15070
ipen.codigoautor8726
ipen.codigoautor12758
ipen.contributor.ipenauthorCAROLINE SANTOS ALVES DE LIMA
ipen.contributor.ipenauthorANA PAULA HONORATO RIBEIRO
ipen.contributor.ipenauthorADEMAR BENEVOLO LUGAO
ipen.contributor.ipenauthorGUSTAVO HENRIQUE COSTAVARCA
ipen.contributor.ipenauthorLUCAS FREITAS DE FREITAS
ipen.contributor.ipenauthorCASSIA PRISCILA CUNHA DA CRUZ
ipen.contributor.ipenauthorJUSTINE PAULA RAMOS DE OLIVEIRA
ipen.contributor.ipenauthorKAMILA MOREIRA NOGUEIRA
ipen.date.recebimento21-03
ipen.event.datapadronizada2020pt_BR
ipen.identifier.ipendoc27642pt_BR
ipen.notas.internasAbstractpt_BR
ipen.type.genreResumo
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sigepi.autor.atividadeLUGAO, A.B.:339:740:Npt_BR
sigepi.autor.atividadeVARCA, G.H.:8661:740:Npt_BR
sigepi.autor.atividadeFREITAS, L.F.:14818:740:Npt_BR
sigepi.autor.atividadeLIMA, C.S.:14945:740:Npt_BR
sigepi.autor.atividadeVARCA, J.O.:8726:740:Npt_BR
sigepi.autor.atividadeNOGUEIRA, K.M.:12758:740:Spt_BR
sigepi.autor.atividadeRIBEIRO, A.H.:15059:740:N
sigepi.autor.atividadeCRUZ, C.C. da:15070:740:N
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