Development of lignin-PVP based dressing for wound treatment
Carregando...
Data
Data de publicação:
2018
Orientador
Título da Revista
ISSN da Revista
Título do Volume
É parte de
É parte de
É parte de
É parte de
CONGRESSO BRASILEIRO DE ENGENHARIA E CIÊNCIA DOS MATERIAIS, 23.
Exportar
Resumo
Lignin is a carbon renewable source and has been widely explored in different fields in
the last years, especially in biomaterials as dressing and other biomedical devices due
its natural origin and low cost1. Poly(ethylene oxide) (PEO) is a synthetic polymer
largely used in biomedical applications due its important characteristics such as high
hydrophilicity, non-toxicity and ease of process2. The present work aimed to develop
a lignin-PEO based dressing for wound treatment by casting. In specific terms, three
different polymer blends were formulated using a range of 3 to 10% (w/v) lignin was
tested with the addition of 1 to 3% PEO. Lignin was solubilized in aqueous solution
(pH>13) alkalized with sodium hydroxide and PEO was solubilized in distilled water.
The solutions were heated up to 70 ºC and homogenized until complete polymer
dissolution. Then, PEO solution and poly(ethylene glycol) diacrylate (PEGDA) (0.5 -
1.0%) were added to the lignin solution and the blend was mixed for 30 minutes at 70
ºC. Posteriorly the blends were submitted to casting and drying under different
conditions, room temperature for 48 hours and incubated at 40 ºC for 24 hours. A
control sample of 6% lignin was prepared in the same conditions. Samples were
evaluated by physico-chemical and morphological characterizations. The swelling and
gel fraction profiles were assessed as well as thermal behavior by differential scanning
calorimetry. Chemical modifications were evaluated by infrared spectroscopy.
Samples with higher PEGDA content presented minor swelling index. The blends
formulated presented different thermal behavior in comparison with the control.
Infrared spectroscopy pointed some chemical modifications promoted by the
crosslinking agent. In general terms, the material developed presented a potential to
continue been explored as dressing for wound treatment
Como referenciar
NOGUEIRA, K.M.; VARCA, J.O.; VARCA, G.H.C.; LIMA, C.S.A.; LUGAO, A.B. Development of lignin-PVP based dressing for wound treatment. In: CONGRESSO BRASILEIRO DE ENGENHARIA E CIÊNCIA DOS MATERIAIS, 23., 04-08 de novembro, 2018, Foz do Iguaçu, PR. Resumo... p. 7289-7289. Disponível em: http://repositorio.ipen.br/handle/123456789/29660. Acesso em: 03 Mar 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.