Using lanthanide chelates and uranyl compounds for diagnostic by fluoroimmunoassays

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dc.contributor.authorSANTOS, ELEN G.pt_BR
dc.contributor.authorTOMIYAMA, CLAUDIA S.pt_BR
dc.contributor.authorKODAIRA, CLAUDIA A.
dc.contributor.authorLOURENCO, ANA V.S.pt_BR
dc.contributor.authorFELINTO, MARIA C.F.C.pt_BR
dc.contributor.authorBRITO, HERMI F.pt_BR
dc.contributor.authorBRITO, MARIA E.F.pt_BR
dc.coverageInternacionalpt_BR
dc.creator.eventoINTERNATIONAL NUCLEAR ATLANTIC CONFERENCE; MEETING ON NUCLEAR APPLICATIONS, 9th; MEETING ON REACTOR PHYSICS AND THERMAL HYDRAULICS, 16th; MEETING ON NUCLEAR INDUSTRY, 1stpt_BR
dc.date.accessioned2014-11-17T18:19:20Zpt_BR
dc.date.accessioned2014-11-18T18:17:42Zpt_BR
dc.date.accessioned2015-04-02T06:16:09Z
dc.date.available2014-11-17T18:19:20Zpt_BR
dc.date.available2014-11-18T18:17:42Zpt_BR
dc.date.available2015-04-02T06:16:09Z
dc.date.eventoSeptember 27 - October 2, 2009pt_BR
dc.description.abstractThe importance of the luminescence of lanthanide ions and UO2 2+ is related to its peculiar characteristics, e.g. long lifetime and line-like emission bands in the visible, which make these ions unique among the species that are known to luminescence. Recent developments in the field of supramolecular chemistry have allowed the design of ligands capable of encapsulating lanthanide ions, thus forming kinetically inert complexes. By introduction of chromophoric groups in these ligands, an intense luminescence of the ion can be obtained via the "antenna effect", defined as a light conversion process involving distinct absorbing (ligand) and emitting (metal ion) components. In such a process, the quantities that contribute to the luminescence intensity are (i) the efficiency of the absorption, (ii) the efficiency of the ligand-metal energy transfer, and (iii) the efficiency of the metal luminescence. Encapsulation of lanthanide ions with suitable ligands may therefore give rise to "molecular devices" capable to emit strong, long-lived luminescence. Besides the intrinsic interest in their excited state properties, compounds of lanthanide ions, in particular of the Eu3+ and Tb3+ ions, and now UO2 2+ are important for their potential use as luminescent labels for biological species in fluoroimmunoassays (FIAs). This is most interesting because fluorimetric labeling represents an alternative method to the use of radioactive labels, which has long been the most common way of quantifying immunoreactions. In this article we report information about luminescent materials, which gave a good signal to quantify biological molecules by TR-FIA, DELFIA , DSLFIA, RIA and FRET.
dc.event.siglaINAC; ENAN; ENFIR; ENINpt_BR
dc.identifier.citationSANTOS, ELEN G.; TOMIYAMA, CLAUDIA S.; KODAIRA, CLAUDIA A.; LOURENCO, ANA V.S.; FELINTO, MARIA C.F.C.; BRITO, HERMI F.; BRITO, MARIA E.F. Using lanthanide chelates and uranyl compounds for diagnostic by fluoroimmunoassays. In: INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE; MEETING ON NUCLEAR APPLICATIONS, 9th; MEETING ON REACTOR PHYSICS AND THERMAL HYDRAULICS, 16th; MEETING ON NUCLEAR INDUSTRY, 1st, September 27 - October 2, 2009, Rio de Janeiro, RJ. <b>Proceedings...</b> Disponível em: http://repositorio.ipen.br/handle/123456789/16547.
dc.identifier.orcidhttps://orcid.org/0000-0001-7028-0878
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/16547pt_BR
dc.local.eventoRio de Janeiro, RJpt_BR
dc.publisherSao Paulo: ABEN, 2009pt_BR
dc.rightsopenAccesspt_BR
dc.subjectchelatespt_BR
dc.subjectefficiencypt_BR
dc.subjectenergy transferpt_BR
dc.subjecteuropium ionspt_BR
dc.subjectimmunoassaypt_BR
dc.subjectlabellingpt_BR
dc.subjectligandspt_BR
dc.subjectluminescencept_BR
dc.subjectrare earthspt_BR
dc.subjectterbium ionspt_BR
dc.subjecturanyl compoundspt_BR
dc.titleUsing lanthanide chelates and uranyl compounds for diagnostic by fluoroimmunoassayspt_BR
dc.typeTexto completo de eventopt_BR
dspace.entity.typePublication
ipen.autorMARIA CLAUDIA FRANCA DA CUNHA FELINTO
ipen.autorCLAUDIA SATIKO TOMIYAMA
ipen.autorELEN GONÇALVES DOS SANTOS
ipen.autorCLAUDIA AKEMI KODAIRA GOES
ipen.codigoautor1103
ipen.codigoautor2572
ipen.codigoautor6049
ipen.codigoautor3969
ipen.contributor.ipenauthorMARIA CLAUDIA FRANCA DA CUNHA FELINTO
ipen.contributor.ipenauthorCLAUDIA SATIKO TOMIYAMA
ipen.contributor.ipenauthorELEN GONÇALVES DOS SANTOS
ipen.contributor.ipenauthorCLAUDIA AKEMI KODAIRA GOES
ipen.date.recebimento09-10pt_BR
ipen.event.datapadronizada2009pt_BR
ipen.identifier.ipendoc15132pt_BR
ipen.notas.internasProceedingspt_BR
ipen.type.genreArtigo
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relation.isAuthorOfPublication63ef6c0f-c20e-4069-9379-e31b34fe0da3
relation.isAuthorOfPublicationce0bcbd5-20a9-407c-9ddf-198b3b9b695c
relation.isAuthorOfPublicationc126e7f7-c223-4380-b3eb-7ada892acb31
relation.isAuthorOfPublication.latestForDiscoveryce0bcbd5-20a9-407c-9ddf-198b3b9b695c
sigepi.autor.atividadeSANTOS, ELEN G.:6049:750:Spt_BR
sigepi.autor.atividadeTOMIYAMA, CLAUDIA S.:2572:-1:Npt_BR
sigepi.autor.atividadeKODAIRA, CLAUDIA A.:3969:-1:Npt_BR
sigepi.autor.atividadeFELINTO, MARIA C.F.C.:1103:750:Npt_BR
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