Characterization by atomic force microscope (AFM) of graphene oxide and graphene oxide-PEG-NH2 incorporated in bovine pericardium

dc.contributor.authorSOARES, JAQUELINE J.S.
dc.contributor.authorCOSTA, CARLOS A.R.
dc.contributor.authorJACOVONE, RAYNARA M.S.
dc.contributor.authorZAIM, MARCIO H.
dc.contributor.authorSAKATA, SOLANGE K.
dc.coverageInternacionalpt_BR
dc.creator.eventoPAN AMERICAN CONGRESS OF NANOTECHNOLOGY, 1stpt_BR
dc.date.accessioned2018-08-14T11:09:19Z
dc.date.available2018-08-14T11:09:19Z
dc.date.evento27-30 de novembro, 2017pt_BR
dc.description.abstractAtomic force microscopy (AFM) is a technique that allows images from the surface topography with high spatial resolution at Nano metric scales. AFM has being used in several fields in science such as Biology, Medicine, Chemistry and Pharmaceuticals. In this study, the tecnhique was used to characterize graphene oxide and graphene oxide functionalized with amino-PEG (GO-PEG-NH2) in the bovine pericardium (BP) surface. The treatment of BP with GO and (GO-PEG-NH2) improved the mechanical properties of the biomaterial that will be used in the manufacture of cardiovascular device that is used to replace heart valves. For the BP coating, two different pathways were tested: 1) chemical pathway using solution containing 1-Ethyl-3- (3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) and GO; and 2) in physical adsorption the incorporation were performed by ultrassom. The same procedure was performed to incorporate GO-PEG-NH2. The images of the BP with its modified surface were obtained by AFM and proof the efficiency in the two incorporation processes. The study also demonstrated the applicability of AFM to characterize incorporated nanomaterial in the biological samples.pt_BR
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)pt_BR
dc.description.sponsorshipIDFAPESP: 17/20177-3pt_BR
dc.event.siglaPANNANOpt_BR
dc.identifier.citationSOARES, JAQUELINE J.S.; COSTA, CARLOS A.R.; JACOVONE, RAYNARA M.S.; ZAIM, MARCIO H.; SAKATA, SOLANGE K. Characterization by atomic force microscope (AFM) of graphene oxide and graphene oxide-PEG-NH2 incorporated in bovine pericardium. In: PAN AMERICAN CONGRESS OF NANOTECHNOLOGY, 1st, 27-30 de novembro, 2017, Guarujá, SP. <b>Abstract...</b> Disponível em: http://repositorio.ipen.br/handle/123456789/29057.
dc.identifier.orcidhttps://orcid.org/0000-0001-6072-5853
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/29057
dc.local.eventoGuarujá, SPpt_BR
dc.rightsopenAccesspt_BR
dc.titleCharacterization by atomic force microscope (AFM) of graphene oxide and graphene oxide-PEG-NH2 incorporated in bovine pericardiumpt_BR
dc.typeResumo de eventos científicospt_BR
dspace.entity.typePublication
ipen.autorSOLANGE KAZUMI SAKATA
ipen.autorRAYNARA MARIA SILVA JACOVONE
ipen.autorJAQUELINE JAMARA SOUZA SOARES
ipen.codigoautor7038
ipen.codigoautor14300
ipen.codigoautor14313
ipen.contributor.ipenauthorSOLANGE KAZUMI SAKATA
ipen.contributor.ipenauthorRAYNARA MARIA SILVA JACOVONE
ipen.contributor.ipenauthorJAQUELINE JAMARA SOUZA SOARES
ipen.date.recebimento18-08pt_BR
ipen.event.datapadronizada2017pt_BR
ipen.identifier.ipendoc24849pt_BR
ipen.notas.internasAbstractpt_BR
ipen.type.genreResumo
relation.isAuthorOfPublicationfb62f288-104d-4352-aed0-a18e0da21a1b
relation.isAuthorOfPublicationda20f0e7-9926-4e06-ae80-ccbc18ec0806
relation.isAuthorOfPublicationcd8afcda-d573-47ce-baa2-ad03bf07b780
relation.isAuthorOfPublication.latestForDiscoverycd8afcda-d573-47ce-baa2-ad03bf07b780
sigepi.autor.atividadeSOARES, JAQUELINE J.S.:14313:220:Spt_BR
sigepi.autor.atividadeJACOVONE, RAYNARA M.S.:14300:220:Npt_BR
sigepi.autor.atividadeSAKATA, SOLANGE K.:7038:220:Npt_BR
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