Tumoural form of Whipple's disease simulating carcinomatosis
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Brazilian Journal of Infectious Diseases
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Whipple’s disease is a rare disease caused by the actinomycete bacteria Tropheryma whipplei, which cause intestinal infection. The most common symptoms are chronic diarrhoea,
weight loss, abdominal pain, arthritis and neurological abnormalities, which can be fatal.
This paper reports a case of a 57-year-old Brazilian woman with diarrhoea, vomiting, abdominal pain, appetite loss, intermittent fever, malaise, weight loss and malnutrition. Migratory
polyarthralgia and recurrent visual scotomas preceded the symptoms. The retroperitoneal
pseudotumour formation finding was associated with prolonged wasting syndrome, which
did not respond to usual therapies, thus leading to the investigation of carcinomatosis disease. After laparotomy, biopsy and histochemical study of the lesions with negative results
for malignancy, we proceeded to the investigation of Whipple’s disease, which was then confirmed. The patient improved clinically and started gaining weight after using ceftriaxone
(IV).
Como referenciar
COSTA, JAMILLE H.S.M.; MACIEL, ALINE B.; GODINHO, MATHEUS de N.G.; PAULA, RAFAELA B. de; GOTARDELO, DANIEL R. Tumoural form of Whipple's disease simulating carcinomatosis. Brazilian Journal of Infectious Diseases, v. n. 18, n. 3, p. 346-349, 2014. DOI: 10.1016/j.bjid.2014.01.006. Disponível em: http://repositorio.ipen.br/handle/123456789/8945. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.