Microspheres for bone regeneration

Página do item simplificado
dc.contributor.authorBORGES, ROGERpt_BR
dc.contributor.authorGENOVA, LUIS A.pt_BR
dc.contributor.authorMARCHI, JULIANApt_BR
dc.contributor.editorFRACETO, LEONARDO F.pt_BR
dc.contributor.editorARAUJO, DANIELE R. dept_BR
dc.coverageInternacionalpt_BR
dc.date.accessioned2020-05-06T13:54:19Z
dc.date.available2020-05-06T13:54:19Z
dc.date.issued2015pt_BR
dc.description.abstractNowadays, with global population aging and habits, cases of fracture, wear and bone loss have constantly concerned health authorities. As an alternative for the recovery of such patients and the promotion of better living conditions, there is a pressing need for development of biomaterials that can successfully replace or regenerate bone tissue. In this research area, microespheres deserve great attention due their unique properties. The specific material and the characteristics of the microspheres to be used for bone regeneration depend on each specific situation, taking into account aspects such as bone characteristics, injury size and selection of the most appropriate technique for such treatment. Generally, microspheres can act as a scaffold for the temporary or permanent filling of the injured area, or may act as a controlled drug delivery system. Moreover, the microspheres can simultaneously fulfill both functions. In this chapter, an overall view of bone tissue is presented, including the structure and functions. The main aspects of bone regeneration are briefly discussed, considering its fracture self-repairing mechanisms through reabsorption and deposition of the mineralized matrix process. When such mechanisms are not enough to provide full recovery, tissue regeneration strategies for such repairs are presented, highlighting the use of biomaterials and specifically microspheres. Finally, some examples of microsphere application to different situations related to the bone regeneration process are discussed.pt_BR
dc.format.extent161-180pt_BR
dc.identifier.capitulo6pt_BR
dc.identifier.citationBORGES, ROGER; GENOVA, LUIS A.; MARCHI, JULIANA. Microspheres for bone regeneration. In: FRACETO, LEONARDO F. (ed.); ARAUJO, DANIELE R. de (ed.). <b>Microspheres: Technologies, Applications and Role in Drug Delivery Systems</b>. Hauppauge, New York, USA: Nova Science Publishers, 2015. , cap. 6. p. 161-180. Disponível em: http://repositorio.ipen.br/handle/123456789/31161.
dc.identifier.orcid0000-0002-5172-5082pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-5172-5082
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/31161
dc.localHauppauge, New York, USApt_BR
dc.publisherNova Science Publisherspt_BR
dc.rightsclosedAccesspt_BR
dc.subjectbone tissues
dc.subjectregeneration
dc.subjectbiological regeneration
dc.subjectskeleton
dc.subjectmicrospheres
dc.subjectdrug delivery
dc.titleMicrospheres for bone regenerationpt_BR
dc.title.livroMicrospheres: Technologies, Applications and Role in Drug Delivery Systemspt_BR
dc.typeCapítulo de livropt_BR
dspace.entity.typePublication
ipen.autorLUIS ANTONIO GENOVA
ipen.codigoautor320
ipen.contributor.ipenauthorLUIS ANTONIO GENOVA
ipen.date.recebimento20-05
ipen.identifier.ipendoc26939pt_BR
ipen.type.genreCapítulo
relation.isAuthorOfPublicatione7af24e8-0db9-49d2-8caf-92fd57c2686b
relation.isAuthorOfPublication.latestForDiscoverye7af24e8-0db9-49d2-8caf-92fd57c2686b
sigepi.autor.atividadeGENOVA, LUIS A.:320:720:Npt_BR
Pacote Original
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
26939.pdf
Tamanho:
906.06 KB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar
Coleções
Capítulos