Osteoarthritis clinical evaluation in patients treated with peruãbe black mud, chemical and radiological characterization and establishment of good practices protocols for the peloid obtainment and use
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2017
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60 YEARS OF IEA-R1: INTERNATIONAL WORKSHOP ON UTILIZATION OF RESEARCH REACTORS
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Resumo
Mudtherapy is the use of peloide (sludge, saline slime and mud) for therapeutic
purposes. Although widely used worldwide its therapeutic mechanisms are not fully
understood, especially considering the different origins and compositions of the used
materials. Several hypotheses have been raised in the attempt to clarify such mechanisms.
Peruãbe Black Mud (PBM) has traditionally been used in the treatment of
osteoarthritis of the knee, which is one of the pathologies of high prevalence and
great impairment of the functional capacity of the patients, through applications of
the peloid in its natural form. This study intends to verify the therapeutic efficacy of
mud, after undergoing a process of decontamination and maturation in marine water,
in patients with knee osteoarthritis, as well as to make a comparison between the
therapeutic effects of the PBM matured and that sterilized by gamma radiation after
maturation. Patients aged between 30 and 85 years, divided into two groups of 20
and 21, respectively, were followed up for a period of 15 weeks. The method of observation
was the double blind. The evaluation was based on subjective information
collected by the WOMAC and SF36 questionnaires as well as X-ray examinations. Simultaneously,
analyzes of the chemical, radiological and microbiological composition
of the PBM were carried out, aiming at a systematized knowledge of the characteristics
of the peloid in relation to possible deleterious effects on human health. X-ray
fluorescence, neutron activation analysis, gamma spectrometry, elemental analysis,
cooling kinetics studies and reduction potential were used to perform these characterizations.
The results obtained allow us to conclude that PBM presents high
levels of Si and S and low levels of Ca, Mg and radioactive elements. None of the
samples matured or irradiated after maturation showed contamination by total coliforms,
thermally tolerant coliforms or staphyloccocus aureus. The results indicate
that there was a decrease in WOMAC and SF36 questionnaire scores for patients
who completed the treatment.
Como referenciar
GOUVEA, P.F.M.; SILVA, P.S.C. Osteoarthritis clinical evaluation in patients treated with peruãbe black mud, chemical and radiological characterization and establishment of good practices protocols for the peloid obtainment and use. In: 60 YEARS OF IEA-R1: INTERNATIONAL WORKSHOP ON UTILIZATION OF RESEARCH REACTORS, November 28 - December 01, 2017, São Paulo, SP. Abstract... São Paulo, SP: Instituto de Pesquisas Energéticas e Nucleares, 2017. p. 45-45. Disponível em: http://repositorio.ipen.br/handle/123456789/28742. Acesso em: 20 Mar 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.