Optical properties of europium tetracycline complexes in the presence of High-Density Lipoproteins (HDL) subfractions

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Applied Spectroscopy
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Standard lipoprotein measurements of triglycerides, total cholesterol, low-density lipoproteins (LDL), and high-density lipoproteins (HDL) fail to identify many lipoprotein abnormalities that contribute to cardiovascular heart diseases (CHD). Studies suggested that the presence of CHD is more strongly associated with the HDL subspecies than with total HDL cholesterol levels. The HDL particles can be collected in at least three subfractions, the HDL2b, HDL2a, and HDL3. More specifically, atherosclerosis is associated with low levels of HDL2. In this work, the optical spectroscopic properties of europium tetracycline (EuTc) complex in the presence of different HDL subspecies was studied. The results show that the europium spectroscopic properties in the EuTc complex are influenced by sizes and concentrations of subclasses. Eu3þ emission intensity and lifetime can discriminate the subfractions HDL3 and HDL2b.

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SICCHIERI, LETICIA B.; MONTEIRO, ANDREA M.; FIGUEIREDO NETO, ANTONIO M.; GOMES, LAERCIO; COURROL, LILIA C. Optical properties of europium tetracycline complexes in the presence of High-Density Lipoproteins (HDL) subfractions. Applied Spectroscopy, v. 71, n. 7, p. 1560-1567, 2017. DOI: 10.1177/0003702816683685. Disponível em: http://repositorio.ipen.br/handle/123456789/27808. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.

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