Chitosan hydrogel containing bioactive glass aiming at 3D printing for tissue engineering
Carregando...
Data
Data de publicação
2023
Autores IPEN
Orientador
Título da Revista
ISSN da Revista
Título do Volume
É parte de
É parte de
É parte de
É parte de
BRAZIL MRS MEETING, 21st
Exportar
Resumo
3D printing is a rising processing technique in tissue engineering due to high reproducibility
and the possibility of complex or even patient-specific models. Chitosan is a promising
biomaterial for both 3D printing and tissue engineering, because of its biocompatibility,
rheological properties, biodegradability, and cost-effectiveness. Bioactive glasses can help the
regeneration of different biological tissues and act as reinforcement for chitosan matrix. In
this work, chitosan hydrogels were produced with different concentrations of 58S
bioactive glass (0.5 up to 5%wt). For the rheological characterization, frequency, and
recovery experiments were carried out. Printability and shape fidelity were evaluated during
the 3D printing process. Indirect cytotoxicity assay using Balb/c 3T3 cells was performed to
evaluate the biological properties of the scaffolds. The presence of the glass maintained the
viscosity properties and increased the recovery percentage. All materials formed filaments
and allowed printing with suitable form maintenance. Biological experiments showed high
cell viability for all 3D scaffolds, even though a reduction was observed for higher glass
concentrations. The results indicate that the studied materials are printable and potentially
recommended for tissue engineering applications.
Como referenciar
LOURENCO, LARISSA R.; BORGES, ROGER; CARASTAN, DANILO J.; MATHOR, MONICA B.; MARCHI, JULIANA. Chitosan hydrogel containing bioactive glass aiming at 3D printing for tissue engineering. In: BRAZIL MRS MEETING, 21st, October 1-5, 2023, Maceió, AL. Abstract... São Carlos, SP: Aptor Software, 2023. p. 349-349. Disponível em: http://repositorio.ipen.br/handle/123456789/34555. Acesso em: 20 Mar 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.