Conceptual proposal of a facility for handlings of minipigs for pharmaceutical and radiopharmaceutical research
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2015
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INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE; MEETING ON NUCLEAR APPLICATIONS, 12th; MEETING ON REACTOR PHYSICS AND THERMAL HYDRAULICS, 19th; MEETING ON NUCLEAR INDUSTRY, 4th
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The use of Animal House Facilities of IPEN-CNEN/SP has provided rats and mice with controlled sanitary
quality for research and quality control in the production of radiopharmaceuticals lots, produced at IPEN,
following rules of CONCEA – Brazilian National Council for Animal Experimentation Control and approved in
Ethics Committee on the Use of Animals (CEUA), before they be sent to hospitals and clinics spread out in
Brazil, for use in Nuclear Medicine. The production and the supply of high quality laboratory animals have
fundamental importance for the accomplishment of vanguard scientific research, with reproducibility and
universality. The quality of those animals depends, largely, of the available facilities for their production and
lodging, to assure the demanded sanitary control and animal’s welfare, in agreement with the ethical principles
that control the activity. Therefore, the facilities design is of vital importance so that the mentioned
requirements can be reached. Nevertheless, pigs and miniature pigs have gained importance as large animal
models in medicine. With their size, organ capacity, and physiology resembling in several aspects that of
humans, pigs are well suited for preclinical experiments and long-term safety studies. The minipigs will be used
for preclinical testing of radiopharmaceuticals and assays radioactive materials for cardiac tests. This paper
describes the premises and preliminary activities that have been performed at IPEN for the design of new
Animal House Facilities dedicated to keeping minipigs taking into account fundamental aspects such as:
animal’s welfare, sanitation, genetic, in agreement with the ethical principles that control the activity and
environmental concerns.
Como referenciar
LAINETTI, ELIZABETH B.F.; SOARES, CARLOS R.J.; NASCIMENTO, NANCI do. Conceptual proposal of a facility for handlings of minipigs for pharmaceutical and radiopharmaceutical research. In: INTERNATIONAL NUCLEAR ATLANTIC CONFERENCE; MEETING ON NUCLEAR APPLICATIONS, 12th; MEETING ON REACTOR PHYSICS AND THERMAL HYDRAULICS, 19th; MEETING ON NUCLEAR INDUSTRY, 4th, October 4-9, 2015, São Paulo, SP. Proceedings... Disponível em: http://repositorio.ipen.br/handle/123456789/26841. Acesso em: 20 Mar 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.