Chitosan-based structures for skin repair

Abstract

The use of chitosan in technological and biomedical applications has gained significant relevance due to its functional properties. Among its biological activities, its hemostatic, analgesic, antibacterial and anti-inflammatory activities make this natural biopolymer one of the most promising in the development of structures for skin repair. Its application and effects can be optimized by exploring efficient structuring techniques. In this context, this review is based on scientific evidence reported in the last decade regarding the development and use of chitosan-based structures in the skin repair process to show the most common structuring methods, the main mechanisms of action of chitosan, and its potential applications in skin repair processes. Additionally, this article brings a compilation of scientific and commercial works on the use of chitosan-based structures, in addition to vitro and/or in vivo results.