Diagnosing lung cancer using etoposide microparticles labeled with 99mTc
Carregando...
Data
Data de publicação
Autores IPEN
Orientador
Título da Revista
ISSN da Revista
Título do Volume
É parte de
É parte de
É parte de
Artificial Cells, Nanomedicine, and Biotechnology
ODS
Exportar
Resumo
The diagnosis of lung cancer mostly occurs when the cancer is already in an advanced stage. In this
situation, there are few options for the treatment and most of them have few chances of success. In
this study, we developed and tested etoposide microparticles as a diagnostic agent for imaging lung
cancer at early stages of development. We tested etoposide microparticles labeled with technetium
99m in inducted mice. The results demonstrated that over 10% of the total dose used was uptake by
the tumor site. Also, the results showed that the microparticles had a good renal clearance and low
uptake by liver and spleen. The data suggest that these micro-radiopharmaceuticals may be used for
lung cancer imaging exam, especially single-photo emission computed tomography (SPECT).
Como referenciar
SALVI, ROBERTO; CERQUEIRA-COUTINHO, CRISTAL; RICCI-JUNIOR, EDUARDO; SANTOS, SOFIA N. dos; PINTO, SUYENE R.; BERNARDES, EMERSON S.; ARAUJO, PATRICIA L.B. de; SANTOS-OLIVEIRA, RALPH. Diagnosing lung cancer using etoposide microparticles labeled with 99mTc. Artificial Cells, Nanomedicine, and Biotechnology, v. 46, n. 2, p. 341-345, 2018. DOI: 10.1080/21691401.2017.1307848. Disponível em: http://repositorio.ipen.br/handle/123456789/28458. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.