Characterization of melt-derived 45S5 and sol-gel-derived 58S bioactive glasses

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Journal of Biomedical Materials Research, B
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The ability of bioactive glasses to form a bond to living bone and also to stimulate bone-cell proliferation depends on the chemical composition and on the surface texture of the glasses. In this work, the differences in physical properties between the melt-derived 45S5 and sol-gel–derived 58S Bioglasst powders of various particle-size ranges were studied. The powders were characterized for particle-size distribution by laser spectrometry, for specific surface area and porosity by nitrogen sorption analysis, and for morphological features by scanning electron microscopy. Melt-derived 45S5 powders exhibited a low-porosity texture with surface area in the range 0.15–2.7 m2 /g. In contrast, the sol-gel–derived powders exhibited a highly mesoporous texture, with surface area in the range of 126.5–164.7 m2 /g and a large fraction of 6–9 nm pore sizes. These differences in texture, as well as variations in chemical composition, account for significant changes in the resorption and in vivo responses.

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SEPULVEDA, PILAR; JONES, JULIAN R.; HENCH, LARRY L. Characterization of melt-derived 45S5 and sol-gel-derived 58S bioactive glasses. Journal of Biomedical Materials Research, B, v. 58, n. 6, p. 734-740, 2001. Disponível em: http://repositorio.ipen.br/handle/123456789/7926. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.

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