Polymeric Nanogels and Nanoparticles in Medical Applications
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Resumo
Nanogels and polymeric nanoparticles have been intensively studied for diverse applications due to their unique and
tuneable properties. Nanogels are hydrogelsdthree-dimensional network of polymer chains with water filling the
spaces between themdin nanometer size, which allows them to penetrate biological barriers and be of high interest
for several medical applications. Polymeric nanoparticles are differentiated from nanogels by the swelling property.
While nanogels have high capacity of water absorption that may lead to size changes, polymeric nanoparticles are
mostly a solid mass. Both, nanogels and nanoparticles may be obtained from synthetic and natural polymers though
different synthesis processes. The radiation-induced intramolecular crosslinking was proposed as a great alternative,
eliminating the need of toxic crosslinking agents and providing a final sterile material. In this review, we intended to present a focused discussion on the radiation-induced synthesis technologies, the most frequent used polymers to
obtain nanogels and nanoparticles, and their biomedical applications showcasing their potential to revolutionize
healthcare.
Como referenciar
KADLUBOWSKI, SLAWOMIR; LIMA, CAROLINE S.A. de; FERREIRA, ARYEL H. Polymeric Nanogels and Nanoparticles in Medical Applications. Materials Science and Materials Engineering. 1 ed. Amesterdã, Países Baixos: Elsevier, 2024. p. 1-23. DOI: 10.1016/B978-0-323-95486-0.00086-7. Disponível em: https://repositorio.ipen.br/handle/123456789/48794. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.