Learning from clinical phenotypes
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Oral Diseases
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This narrative review on the use of biophotonics therapies for management of oral
diseases is written as a tribute to Prof. Crispian Scully. His seminal contributions to the
field are highlighted by the detailed, comprehensive description of clinical presentations
of oral diseases. This has enabled a more thorough, fundamental understanding
of many of these pathologies by research from his group as well as inspired mechanistic
investigations in many groups globally. In the same vein, a major emphasis of this
narrative review is to focus on the evidence from human case reports rather than in
vitro or in vivo animal studies that showcases the growing and broad impact of biophotonics
therapies. The similarities and differences between two distinct forms of
low-dose
biophotonics treatments namely photodynamic therapy and photobiomodulation
therapy are discussed. As evident in this review, a majority of these reports
provide promising evidence for their clinical efficacy. However, a lack of adequate
technical details, precise biological rationale, and limited outcome measures limits the
current utility of these treatments. Future investigations should attempt to address
these shortcomings and develop better designed, rigorous, controlled studies to fully
harness the tremendous potential of low-dose
biophotonics therapies.
Como referenciar
RAHMAN, S.U.; MOSCA, R.C.; REDDY, S.G.; NUNEZ, S.C.; ANDREANA, S.; MANG, T.S.; ARANY, P.R. Learning from clinical phenotypes: low-dose biophotonics therapies in oral diseases. Oral Diseases, v. 24, n. 1-2, p. 261-276, 2018. DOI: 10.1111/odi.12796. Disponível em: http://repositorio.ipen.br/handle/123456789/29027. Acesso em: 20 Mar 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.