Nutraceutical compound increases collagen, elastin and hyaluronic acid synthesis
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Surgical & Cosmetic Dermatology
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Introduction: The use of nutraceutical products in order to attenuate signs of skin aging
has been proposed in the literature. The stimulus to the synthesis of substances that support
the dermis is one of the mechanisms linked to this effect.
Objective: To evaluate the effectiveness of a nutraceutical compound containing lutein,
lycopene, vitamin C and manganese for the synthesis of collagen, elastin and hyaluronic acid.
Methods: An in vitro study was carried out based on the culture of human fibroblasts
treated with the investigated product in different non-cytotoxic concentrations. The quantification
of the elastin and collagen was performed with the assistance of spectrophotometric
measurements. Hyaluronic acid was measure using a immunoenzymatic method.
Results: Cell cultures treated with the different concentrations of the product showed a
significantly higher amount of synthesized collagen, elastin and hyaluronic acid as compared
to the untreated culture (p <0.05).
Conclusions: The use of the nutraceutical compound containing lycopene, vitamin C,
lutein and manganese has shown in vitro efficacy for stimulating the synthesis of collagen,
elastin and hyaluronic acid, components that are crucial for providing the dermis’ supporting
structure, being responsible for the skin’s firmness and elasticity
Como referenciar
SCHALKA, SERGIO; MAGALHAES, WAGNER V.; CAZERTA, CAMILA; SHITARAC, DANIELLE; SUFI, BIANCA da S.; QUADROS, ANANDA. Nutraceutical compound increases collagen, elastin and hyaluronic acid synthesis. Surgical & Cosmetic Dermatology, v. 09, n. 01, p. 46-50, 2017. DOI: 10.5935/scd1984-8773.201791875. Disponível em: http://repositorio.ipen.br/handle/123456789/28530. Acesso em: 20 Mar 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.