Influence of argon and nitrous oxide on the synthesis of PVP nanogels prepared by gamma radiation

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dc.contributor.authorBALOGH, T.S.pt_BR
dc.contributor.authorKADLUBOWSKI, S.pt_BR
dc.contributor.authorBONTURIM, E.pt_BR
dc.contributor.authorLUGAO, A.B.pt_BR
dc.contributor.authorVARCA, G.H.pt_BR
dc.coverageInternacionalpt_BR
dc.creator.eventoPAN-AMERICAN NANOTECHNOLOGY CONFERENCE, 2ndpt_BR
dc.date.accessioned2021-03-05T19:12:46Z
dc.date.available2021-03-05T19:12:46Z
dc.date.eventoMarch 4-7, 2020pt_BR
dc.description.abstractNanogels are innovative systems with great potential for use in chemotherapy, disease diagnosis, release of bioactive substances, vaccines, cell culture systems, biocatalysis, in the generation of bioactive scaffolds in regenerative medicine among other applications. The definition of this material can be directly derived from the definition of polymeric gel, that is, a two-component system consisting of a permanent three-dimensional network of linked polymer chains and solvent molecules filling the pores of this network. Its internal structure is similar to that of hydrogels however presents particle size range varying from 0 to 100 nm leading to several advantages. Nanogel production methods involve intramolecular crosslinking that can be achieved using ionizing radiation. This method avoids the addition of any additives allowing the reaction to be carried out in a pure polymer-solvent system and the production of nanogels for biomedical applications free from monomer and crosslinking agents or surfactants. In this work influence of argon and nitrous oxide on the formation of nanogels by gamma irradiation has been evaluated. The samples were prepared in duplicate in multipurpose cobalt-60 gamma irradiator using a 25 mM PVP solution. Samples were irradiated in argon and nitrous oxide conditions with doses from 1 kGy up to 25 kGy with 10 kGy/h dose rate. These samples were morphologically characterized using Scanning Electron Microscopy (SEM) and Atomic Force Microscopy (AFM) as well as the pristine PVP solution. The mean particle size of the samples and the polydispersity index was performed in equipment Zetasizer Nano ZS - Malvern® and the determination of radius of gyration and molecular weight was performed in equipment Heleos - Wyatt®. It was observed in the conditions evaluated that saturation with argon or nitrous oxide promoted similar results except for 25 kGy dose. At this dose larger mean particle size and radius of gyration were observed in the sample saturated with nitrous oxide.pt_BR
dc.event.siglaPANNANOpt_BR
dc.identifier.citationBALOGH, T.S.; KADLUBOWSKI, S.; BONTURIM, E.; LUGAO, A.B.; VARCA, G.H. Influence of argon and nitrous oxide on the synthesis of PVP nanogels prepared by gamma radiation. In: PAN-AMERICAN NANOTECHNOLOGY CONFERENCE, 2nd, March 4-7, 2020, Águas de Lindoia, SP. <b>Abstract...</b> Disponível em: http://repositorio.ipen.br/handle/123456789/31883.
dc.identifier.orcid0000-0002-6545-237Xpt_BR
dc.identifier.orcid0000-0002-1737-3191pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1737-3191
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/31883
dc.local.eventoÁguas de Lindoia, SPpt_BR
dc.rightsopenAccesspt_BR
dc.titleInfluence of argon and nitrous oxide on the synthesis of PVP nanogels prepared by gamma radiationpt_BR
dc.typeResumo de eventos científicospt_BR
dspace.entity.typePublication
ipen.autorGUSTAVO HENRIQUE COSTAVARCA
ipen.autorADEMAR BENEVOLO LUGAO
ipen.autorTATIANA SANTANA BALOGH
ipen.codigoautor8661
ipen.codigoautor339
ipen.codigoautor14431
ipen.contributor.ipenauthorGUSTAVO HENRIQUE COSTAVARCA
ipen.contributor.ipenauthorADEMAR BENEVOLO LUGAO
ipen.contributor.ipenauthorTATIANA SANTANA BALOGH
ipen.date.recebimento21-03
ipen.event.datapadronizada2020pt_BR
ipen.identifier.ipendoc27654pt_BR
ipen.notas.internasAbstractpt_BR
ipen.type.genreResumo
relation.isAuthorOfPublication46f998cf-b207-4854-94c0-dd2def4eec2a
relation.isAuthorOfPublication99ac24c5-2ae1-465a-a6f2-40b4d9af6af7
relation.isAuthorOfPublicationb1f1c387-fb7b-4445-93d5-678576c4aa8d
relation.isAuthorOfPublication.latestForDiscoveryb1f1c387-fb7b-4445-93d5-678576c4aa8d
sigepi.autor.atividadeVARCA, G.H.:8661:740:Npt_BR
sigepi.autor.atividadeLUGAO, A.B.:339:740:Npt_BR
sigepi.autor.atividadeBALOGH, T.S.:14431:740:Spt_BR
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