Evaluation of DEET cytotoxicity on Perna perna mussels
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Data
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2014
Autores IPEN
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É parte de
ANNUAL MEETING OF THE SOCIETY OF ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 24th
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Resumo
Recent studies have identified the presence of several emerging pollutants in
aquatic environments. The occurrence in different environmental matrices has been
continuously reported, highlighting the need for toxicity studies. Developed in the
1940s and present in many commercially available formulations, the DEET
(N,N-diethyl-meta-toluamide) is the active agent used in most insect repellents.
Several studies have been identified the DEET presence in surface water and in
wastewater treatment plant (WWTP) effluent, so this compound is considered an
emerging pollutant and studies indicate that DEET is only slightly toxic to aquatic
organisms. Even nowadays the environmental destiny of DEET is not completely
understood. Although DEET is considered a compound resistant to degradation and
commonly found in surface water, there are not complete assessments for
ecological risk of DEET, including studies evaluating chronic toxicity to aquatic
organisms. In this study was evaluated the DEET toxicity and the effects caused in
lysosomes of Perna perna mussels hemocytes. For this purpose, firstly was
performed the acute toxicity assay to identify the DEET concentration that causes
50% mortality of exposed organisms to DEET concentrations in the range of 75 to
400 mg L-1 and the obtained lethal dose (LC50) was 114.27 mg L-1. To assess the
stability of the lysosomal membrane in organisms exposed to this compound was
carried out the cytotoxicity assay utilizing DEET concentrations in a range of 0.001
to 1.0 mg L-1. In fact, is important reinforce that the data of DEET cytotoxicity
showed disturbances in Perna perna mussels in all tested concentrations.
Como referenciar
MARTINI, G.D.; ROGERO, S.O.; AZEVEDO, J.D.; ROGERO, J.R. Evaluation of DEET cytotoxicity on Perna perna mussels. In: ANNUAL MEETING OF THE SOCIETY OF ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 24th, May 11-15, 2014, Basel, Switzerland. Abstract... p. 164-164. Disponível em: http://repositorio.ipen.br/handle/123456789/27658. Acesso em: 20 Mar 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.