In vitro effect of innovative desensitizing agents on dentin tubule occlusion and erosive wear
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Operative Dentistry
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Purpose: The purpose of this study was to
evaluate the effects of four in-office desensitizing
products on dentin tubule occlusion and
erosive wear.
Methods: Dentin hypersensitivity was simulated
by EDTA application for five minutes. The
specimens were randomly allocated into five
groups (n=11), according to treatment:No treatment
- Control (C), Duraphat (DUR), Desensibilize
Nano P (NP), ClinPro XT Varnish (XTV), and ClinPro White Varnish (CWV). They were then
submitted to erosive/abrasive cycling for five
days. After EDTA, treatment, and cycling, the
specimens were analyzed with an environmental
scanning electron microscope (ESEM) to
verify the number of opened dentin tubules
(ODT) which were counted by using ImageJ
software, and with a profilometer to determine
the surface curvature/loss. ESEM data were
analyzed with two-way repeated measure analysis
of variance and Tukey tests. For the profilometer,
data were analyzed with Kruskal-
Wallis, Tukey, and Mann-Whitney tests.
Results: After treatment, all groups showed
lower ODT than the control, without significant differences between them. After cycling,
the only group that showed lower ODT than
the control was group XTV; however, it did not
significantly differ from the other groups. For
the profilometric analysis, there were significant
differences in SL between the experimental
times after treatment and after cycling for
all groups (p,0.05). After cycling, no surface
loss was detected in groups DUR and XTV,
which presented a significantly different curvature
than group NP and the control group,
but not from group CWV. Surface loss was
detected for the control and groups NP and
CWV, without difference among them.
Conclusion: All desensitizing agents tested
presented promising results concerning the
obliteration of dentin tubules immediately
after treatment. XTV was the only desensitizer
capable of preventing the reopening of the
tubules after the erosive/abrasive challenges.
XTV and DUR presented a protective effect
against dentin erosive wear.
Como referenciar
GAROFALO, S.A.; SAKAE, L.O.; MACHADO, A.C.; CUNHA, S.R.; ZEZELL, D.M.; SCARAMUCCI, T.; ARANHA, A.C. In vitro effect of innovative desensitizing agents on dentin tubule occlusion and erosive wear. Operative Dentistry, v. 44, n. 2, p. 168-177, 2019. DOI: 10.2341/17-284-L. Disponível em: http://repositorio.ipen.br/handle/123456789/30436. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.