On the feasibility of producing Lu-177 in the IEA-R1 reactor via the direct route
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Brazilian Journal of Radiation Sciences
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Over the last years the 177Lu radioisotope has attracted great interest for the use in therapeutic and diagnostic procedures simultaneously, being what is now called a theranostic radioisotope, with outstanding results in prostate and neuroendocrine cancer. There are mainly two ways of producing this radioisotope, by direct neutron capture in a 176Lu target (the “direct route") or by irradiating a 176Yb sample, producing 177Yb that will then decay to 177Lu (also referred as the “indirect route”). In this work, the technical feasibility of producing 177Lu in the IEA-R1 nuclear research reactor via the direct route was assessed, and the specific activity that could be obtained was estimated both experimentally and theoretically.
Como referenciar
ZAHN, G.S.; GENEZINI, F.A.; SILVA, P.S.C.; NORY, R.M.; MOREIRA, E.G.; SANTIAGO, P.S. On the feasibility of producing Lu-177 in the IEA-R1 reactor via the direct route. Brazilian Journal of Radiation Sciences, v. 9, n. 1A, p. 1-11, 2021. DOI: 10.15392/bjrs.v9i1A.1411. Disponível em: http://repositorio.ipen.br/handle/123456789/32111. Acesso em: 27 Mar 2026.
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