Recombinant thyrotropin containing a beta-subunit chimera with the human chorionic gonadotropin-beta carboxy-terminus Is biologically active, with a prolonged plasma half-life. Role of carbohydrate in bioactivity and metabolic clearance

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dc.contributor.authorJOSHI, L.pt_BR
dc.contributor.authorMURATA, Y.pt_BR
dc.contributor.authorWONDISFORD, F.E.pt_BR
dc.contributor.authorSZKUDLINSKI, M.W.pt_BR
dc.contributor.authorDESAI, R.pt_BR
dc.contributor.authorWEINTRAUB, B.D.pt_BR
dc.coverageInternacionalpt_BR
dc.date.accessioned2014-07-31T11:32:40Zpt_BR
dc.date.accessioned2014-07-31T11:58:02Z
dc.date.available2014-07-31T11:32:40Zpt_BR
dc.date.available2014-07-31T11:58:02Z
dc.date.issued1995pt_BR
dc.format.extent3839-3848pt_BR
dc.identifier.citationJOSHI, L.; MURATA, Y.; WONDISFORD, F.E.; SZKUDLINSKI, M.W.; DESAI, R.; WEINTRAUB, B.D. Recombinant thyrotropin containing a beta-subunit chimera with the human chorionic gonadotropin-beta carboxy-terminus Is biologically active, with a prolonged plasma half-life. Role of carbohydrate in bioactivity and metabolic clearance. <b>Endocrinology</b>, v. 136, n. 9, p. 3839-3848, 1995. Disponível em: http://repositorio.ipen.br/handle/123456789/6911.
dc.identifier.fasciculo9pt_BR
dc.identifier.issn0013-7227pt_BR
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/6911pt_BR
dc.identifier.vol136pt_BR
dc.relation.ispartofEndocrinologypt_BR
dc.rightsclosedAccessen
dc.subjecttshpt_BR
dc.subjectrecombinationpt_BR
dc.subjectpeptidespt_BR
dc.subjectchimeraspt_BR
dc.subjectplasmapt_BR
dc.subjectbiological half-lifept_BR
dc.subjectsialic acidpt_BR
dc.titleRecombinant thyrotropin containing a beta-subunit chimera with the human chorionic gonadotropin-beta carboxy-terminus Is biologically active, with a prolonged plasma half-life. Role of carbohydrate in bioactivity and metabolic clearancept_BR
dc.typeArtigo de periódicopt_BR
dspace.entity.typePublication
ipen.autorYOKO MURATA
ipen.codigoautor463
ipen.contributor.ipenauthorYOKO MURATA
ipen.date.recebimento96-01pt_BR
ipen.identifier.ipendoc02828pt_BR
ipen.identifier.iwosWoSpt_BR
ipen.type.genreArtigo
relation.isAuthorOfPublication6a0ad37a-6ed4-455b-8d0f-7dfd07b6799d
relation.isAuthorOfPublication.latestForDiscovery6a0ad37a-6ed4-455b-8d0f-7dfd07b6799d
sigepi.autor.atividadeJOSHI, L.:-1:-1:Spt_BR
sigepi.autor.atividadept_BR
sigepi.autor.atividadeMURATA, Y.:463:-1:Npt_BR
sigepi.autor.atividadeWONDISFORD, F.E.:-1:-1:Npt_BR
sigepi.autor.atividadept_BR
sigepi.autor.atividadept_BR
sigepi.autor.atividadeSZKUDLINSKI, M.W.:-1:-1:Npt_BR
sigepi.autor.atividadeDESAI, R.:-1:-1:Npt_BR
sigepi.autor.atividadept_BR
sigepi.autor.atividadeWEINTRAUB, B.D.:-1:-1:Npt_BR
sigepi.autor.atividadept_BR

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