Analytic techniques to assist the antivenom production in Brazil
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2016
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REUNIÃO DE TRABALHO SOBRE FÍSICA NUCLEAR NO BRASIL, 39.
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Resumo
According to World Health Organization (WHO) the number of deaths by poisonous animals in
developed countries is significant. The situation in Brazil has been monitored by SINAN (Sistema
de Informação de Agravos e Notificação) and currently 400 accidents occur every month, of which
80% are due to venomous snakebites of the genus Bothrops. To meet the large number of
incidences, Instituto Butantan (research center, at Brazil) has produced various types of
antivenomous including anti-Bothrops serum. However, the high diversity of snakes (~380
species), a large portion of them being venomous, it can sometimes result of an inappropriate
antivenom. In addition, recent investigation showed that the Bothrops venom of certain species can
vary significantly according to geographic distribution (in the Northern region the snake poison of
jararaca is 30 times more potent than that found in the Southeast region). In this study, the inorganic
elements concentration in blood of mice immunized with different species of Bothrops snake
venoms were investigated using NAA and XRF techniques. Comparing the results permit to assess
whether it is possible to use a single anti-Bothrops serum. Moreover, these results were compared
with human estimative to prevent damage due to toxicity of these elements in the immunological
therapy.
Como referenciar
METAIRON, S.; ZAMBONI, C.B.; SUZUKI, M.F. Analytic techniques to assist the antivenom production in Brazil. In: REUNIÃO DE TRABALHO SOBRE FÍSICA NUCLEAR NO BRASIL, 39., 03-07 de setembro, 2016, Natal, RN. Abstract... Disponível em: http://repositorio.ipen.br/handle/123456789/27605. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.