Multifunctional bioactive glasses for tissue regeneration: compositions modified with strontium oxide
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2017
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INTERNATIONAL CONFERENCE ON DIFFUSION IN SOLIDS AND LIQUIDS, 13th
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The complexity in designing brand-new compositions as 45S5 Bioglass® is mainly due to the fact the more components you have, the more difficult it is to trace the relationship between composition, structure and bioactivity. Also, the properties of bioactive compositions should reflect directly their ability to release a critical amount of different ions in the surrounding host material, creating or not favorable conditions for the cellular processes. The present research was conducted by modifying the glass network of 45S5 by adding Al2O3 and SrO in order to obtain a multifunctional glass for biomedical applications, i.e. a not only with bioactive properties as osteoinductive and also biocidal. Three series of compositions were produced to optimized the amounts of both oxides, thus, minimizing undesirable effects and enhancing the mobility of Ca2+ cations due to the rearrangement of the glass network. The samples were obtained by melting (1500°C) and quenching and characterized by X-ray diffraction (XRD), differential thermal analysis (ATD), Fourier transform infrared (FTIR) and Raman spectroscopy. The initial results indicates that the vitreous network is predominantly of Q3 arrangements in detriment of the typical 45S5 Q2 structure. And, the FT-IR and Raman spectra are similar to glasses with adequate solubility and bioactivity for the interaction between the implant and the host.
Como referenciar
ARAUJO, M.S.; SILVA, A.C.; SILVA, D.L.C. e; MELLO-CASTANHO, S.R.H. Multifunctional bioactive glasses for tissue regeneration: compositions modified with strontium oxide. In: DSL CONFERENCE (ed.). In: INTERNATIONAL CONFERENCE ON DIFFUSION IN SOLIDS AND LIQUIDS, 13th, June 26-30, 2017, Vienna, Austria. Abstract... p. 121-121. Disponível em: http://repositorio.ipen.br/handle/123456789/27713. Acesso em: 28 Mar 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.