The effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEG

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dc.contributor.authorSOARES, J.J.S.pt_BR
dc.contributor.authorJACOVONE, R.M.S.pt_BR
dc.contributor.authorSANTOS, P.S.pt_BR
dc.contributor.authorZAIM, M.H.pt_BR
dc.contributor.authorFARIA, D.L.A.pt_BR
dc.contributor.authorSAKATA, S.K.pt_BR
dc.coverageNacionalpt_BR
dc.date.accessioned2019-12-20T13:25:14Z
dc.date.available2019-12-20T13:25:14Z
dc.date.issued2019pt_BR
dc.description.abstractCovalent functionalization of graphene oxide (GO) with polyethylene glycol (PEG) has been widely used in drug delivery systems. This nanocomposite exhibits excellent stability in the presence of high concentrations of salts and proteins and shows low toxicity compared to its raw form. However, it must be sterilized prior to use in medical devices, and for this purpose, the gamma irradiation shows a promising option. Sterilization by ionizing energy through gamma rays, generated by Cobalt-60 self-disintegration, consists in exposing the materials to short electromagnetic waves. The irradiation process provides substantial advantages when compared to thermal and chemical processes, such as, more precise control of the process, lower energy consumption, and less environmental pollution. In this work the effects of gamma radiation on GO and GO functionalized with amino-PEG (GO-PEG-NH2) irradiated with doses (15, 25, 35 and 50 kGy) at rate dose of 7.3 kGy.h-1 were evaluated. The analyses were performed by Fourier-transform infrared spectroscopy (FT-IR) and Raman spectroscopy. The results showed that gamma radiation up to 50 kGy did not cause any defects on the nanomaterials.pt_BR
dc.format.extent1-12pt_BR
dc.identifier.citationSOARES, J.J.S.; JACOVONE, R.M.S.; SANTOS, P.S.; ZAIM, M.H.; FARIA, D.L.A.; SAKATA, S.K. The effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEG. <b>Brazilian Journal of Radiation Sciences</b>, v. 7, n. 3, p. 1-12, 2019. DOI: <a href="https://dx.doi.org/10.15392/bjrs.v7i3.837">10.15392/bjrs.v7i3.837</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/30484.
dc.identifier.doi10.15392/bjrs.v7i3.837pt_BR
dc.identifier.fasciculo3pt_BR
dc.identifier.issn2319-0612pt_BR
dc.identifier.orcid0000-0001-6072-5853pt_BR
dc.identifier.orcid0000-0002-2112-4139pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-6072-5853
dc.identifier.percentilfiSem Percentilpt_BR
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/30484
dc.identifier.vol7pt_BR
dc.relation.ispartofBrazilian Journal of Radiation Sciencespt_BR
dc.rightsopenAccesspt_BR
dc.subjectcobalt 60
dc.subjectdose rates
dc.subjectfourier transformation
dc.subjectgamma radiation
dc.subjectgraphene
dc.subjectinfrared spectra
dc.subjectpolyethylene glycols
dc.subjectradiation doses
dc.subjectradiation effects
dc.subjectraman spectroscopy
dc.subjectsterilization
dc.subjectsynthesis
dc.titleThe effect of gamma radiation on the structure of graphene oxide and graphene oxide functionalized with amino-PEGpt_BR
dc.typeArtigo de periódicopt_BR
dspace.entity.typePublication
ipen.autorPAULO DE SOUZA SANTOS
ipen.autorSOLANGE KAZUMI SAKATA
ipen.autorRAYNARA MARIA SILVA JACOVONE
ipen.autorJAQUELINE JAMARA SOUZA SOARES
ipen.codigoautor4074
ipen.codigoautor7038
ipen.codigoautor14300
ipen.codigoautor14313
ipen.contributor.ipenauthorPAULO DE SOUZA SANTOS
ipen.contributor.ipenauthorSOLANGE KAZUMI SAKATA
ipen.contributor.ipenauthorRAYNARA MARIA SILVA JACOVONE
ipen.contributor.ipenauthorJAQUELINE JAMARA SOUZA SOARES
ipen.date.recebimento19-12
ipen.identifier.fiSem F.I.pt_BR
ipen.identifier.ipendoc26514pt_BR
ipen.type.genreArtigo
relation.isAuthorOfPublication580f004e-82b5-446f-8853-cc50707b42fd
relation.isAuthorOfPublicationfb62f288-104d-4352-aed0-a18e0da21a1b
relation.isAuthorOfPublicationda20f0e7-9926-4e06-ae80-ccbc18ec0806
relation.isAuthorOfPublicationcd8afcda-d573-47ce-baa2-ad03bf07b780
relation.isAuthorOfPublication.latestForDiscoverycd8afcda-d573-47ce-baa2-ad03bf07b780
sigepi.autor.atividadeSAKATA, S.K.:7038:220:Npt_BR
sigepi.autor.atividadeSANTOS, P.S.:4074:240:Npt_BR
sigepi.autor.atividadeJACOVONE, R.M.S.:14300:220:Npt_BR
sigepi.autor.atividadeSOARES, J.J.S.:14313:220:Spt_BR
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