Pediatric burn treatment using tilapia skin as a xenograft for superficial partial-thickness wounds
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Journal of Burn Care & Research
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This study aims to evaluate the efficacy of Nile tilapia skin as a xenograft for the treatment of partial-thickness
burn wounds in children. This is an open-label, monocentric, randomized phase II pilot study conducted
in Fortaleza, Brazil. The study population consisted of 30 children between the ages of 2 and 12 years with
superficial “partial-thickness” burns admitted less than 72 hours from the thermal injury. In the test group, the
tilapia skin was applied. In the control group, a thin layer of silver sulfadiazine cream 1% was applied. Tilapia
skin showed good adherence to the wound bed, reducing the number of dressing changes required, the amount
of anesthetics used, and providing benefits for the patients and also for healthcare professionals, by reducing the
overall work load. The number of days to complete burn wound healing, the total amount of analgesics required
throughout the treatment, burn improvement on the day of dressing removal, and pain throughout the treatment
were similar to the conventional treatment with silver sulfadiazine. Thus, tilapia skin can be considered an
effective and low-cost extra resource in the therapeutic arsenal of pediatric superficial partial thickness burns.
Como referenciar
LIMA JUNIOR, EDMAR M.; MORAES FILHO, MANOEL O. de; FORTE, ANTONIO J.; COSTA, BRUNO A.; FECHINE, FRANCISCO V.; ALVES, ANA P.N.N.; MORAES, MARIA E.A. de; ROCHA, MARINA B.S.; SILVA JUNIOR, FRANCISCO R.; SOARES, MARIA F.A. do N.; BEZERRA, ALANE N.; MARTINS, CAMILA B.; MATHOR, MONICA B. Pediatric burn treatment using tilapia skin as a xenograft for superficial partial-thickness wounds: a pilot study. Journal of Burn Care & Research, v. 41, n. 2, p. 241-247, 2020. DOI: 10.1093/jbcr/irz149. Disponível em: http://repositorio.ipen.br/handle/123456789/31825. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.