Influence of space holder on the biocompatibility of Ti-34Nb-6Sn alloy prepared by powder metallurgy
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2019
Autores IPEN
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INTERNATIONAL MATERIALS RESEARCH CONGRESS, 28th
Resumo
Development of metallic materials for denistry and orthoapedic area have been increasing, due to in
world life expectancy and the significantly numbers of accide nts. Due to problems of failure in
available commercial materials implantation, as well as the discomfort of patient because the high
elastic modulus, these devices need to be improved or news implants should be sought. This study
was intended to develop a porous alloy, Ti-34-Nb-6Sn/Mg wich can help the ingrowth bone tissue
when implanted, by the powder metallurgy. After the milling powders in the high energy mill, were
compacted and sintered. Both, powders and sintered materials were chacarterized by X-ray Difraction
(XRD), Scanning Electron Microscopy (SEM) and semi-quantitative compositional analysis (EDS). The
apparent porosity was measured through the Arquimed’s Method. The toxicity this material was
evaluated by MTT assay, using the equine mesenchemal stem cells derivated of bone marrow
(bmMSC) according to ISO 109935. The bmMSCs morphological analysis in contact on the material
surface using SEM. The Mg evaporation was confirmed by EDS and XRD after sintering. The XRD
indicate there is predominantly beta phase than alpha. The apparent porosity was higher in alloy with
Mg space holder. The materials do not presented particular cytotoxic in direct and indirect contact.
Metallurgic powder tecnhique promoted effectively macropores formation in Ti-34Nb-6Sn/Mg alloy,
wich possibly further bmMSCs adhesion.
Como referenciar
ROSSI, MARIANA C.; BAYERLEIN, DANIEL L.; KRIECK, ANDRE M.T.; BRANDÃO, JAQUELINE de S.; PFEIFER, JOÃO P.H.; ROSA, GUSTAVO dos S.; STIEVANI, FERNANDA de C.; MARTINEZ, LUIS G.; SAEKI, MARGARIDA J.; ALVES, ANA L.G. Influence of space holder on the biocompatibility of Ti-34Nb-6Sn alloy prepared by powder metallurgy. In: INTERNATIONAL MATERIALS RESEARCH CONGRESS, 28th, August 18-23, 2019, Cancun, México. Abstract... Ciudad de México, México: Sociedad Mexicana de Materiales, 2019. Disponível em: http://repositorio.ipen.br/handle/123456789/31009. Acesso em: 29 Apr 2026.
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