A new natural detector for irradiations with blue LED light source in photodynamic therapy measurements via UV–Vis spectroscopy
Carregando...
Data
Data de publicação
Autores IPEN
Orientador
Título da Revista
ISSN da Revista
Título do Volume
É parte de
É parte de
É parte de
Photochemical and Photobiological Sciences
Exportar
Resumo
Photodynamic therapy has been recently studied, bringing innovations regarding the reduction of exposure time to light by the patient. This work aimed to investigate the feasibility of using Coutarea hexandra (Jacq.) K. Schum (CHS) as a detector in photodynamic therapy measurements. For this, an irradiator containing a blue LED bulb lamp was utilized. The CHS samples were irradiated with ten doses from 0.60 up to 6.0 kJ/cm2, and six concentrations were prepared (1, 2, 3, 4, 5, and 6 mg/ml) for the CHS detector samples. After irradiation, the detector samples were evaluated using UV–Vis spectrophotometry. The results showed the behavior of the CHS detector with doses and concentrations, its sensitivity, and its linearity was also evaluated both by Wavelength Method (WM) and the Kernel Principal Component Regression (KPCR) Statistical Method. The values obtained indicate that this method can be applied to the CHS sample detector. In conclusion, the CHS is a promising detector in the field of photodynamic therapy.
Como referenciar
OLIVEIRA, LUCAS N. de; NASCIMENTO, ERIBERTO O. do; CALDAS, LINDA V.E. A new natural detector for irradiations with blue LED light source in photodynamic therapy measurements via UV–Vis spectroscopy. Photochemical and Photobiological Sciences, v. 20, n. 11, p. 1381-1395, 2021. DOI: 10.1007/s43630-021-00088-w. Disponível em: http://repositorio.ipen.br/handle/123456789/32377. Acesso em: 24 Mar 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.