Association of antimicrobial photodynamic therapy (aPDT) and platelet- and leukocyte-rich fibrin (L-PRF) in immediate dental implant surgery in contaminated alveoli with extensive bone loss
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Advances in Clinical and Experimental Medicine
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In patients with extensive bone loss, dental implants are a challenge for oral rehabilitation. The presence
of dental infection requires prior resolution with several surgical steps. Local decontamination after tooth
extraction, using antimicrobial photodynamic therapy (aPDT – low-level laser: 660 nm, 100 mW, 60 s, 6 J,
Laser Duo, MM Optics, SP/Brazil; methylene blue 0.01%, Chimiolux 10 – DMC, SP/Brazil), followed by the release
of growth factors and angiogenesis stimulation achieved by the use of platelet- and leukocyte-rich
fibrin (L-PRF), have the potential to reduce the number of surgical interventions, being safe for patients, even
in the presence of systemic diseases. The Hounsfield index variation was evaluated using the Dental Slice
software (BioParts) in cone-beam computed tomography scans, performed before and 3 months after dental
implant surgery (ArcsysFGM, SC/Brazil) in patients who had extensive bone loss with the presence of local
infection and underwent local decontamination with aPDT and the use of L-PRF (hydration of the xenogenous
graft and membrane to protect the surgical area). The change in ROI cross-sectional areas was also compared
using ImageJ software before and after 3 months. The torque evaluation with the aid of the system ratchet
(35 N) was assessed after the exposure of the implants, without pain, sowing the stability of the implants. With
the association of these techniques in a single surgical moment, there was osseointegration of the implants,
showing the potential of this protocol in critical areas, reducing the number of surgical interventions and
medications (anesthesia, antibiotics, anti-inflammatories, analgesics), improving the quality of life of patients
in a reduced time interval compared to the conventional protocol. Systemically compromised patients, such
as those with heart disease and diabetes, may be particularly favored.
Como referenciar
MORAES, PAULO N.L. de; DIAS-MORAES, MARCIA C.; ZEZELL, DENISE M. Association of antimicrobial photodynamic therapy (aPDT) and platelet- and leukocyte-rich fibrin (L-PRF) in immediate dental implant surgery in contaminated alveoli with extensive bone loss. Advances in Clinical and Experimental Medicine, v. 32, n. Special Issue 4, p. 216-216, 2023. DOI: 10.17219/acem/2023-laserdentistry-abstractbook. Disponível em: https://repositorio.ipen.br/handle/123456789/48149. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.