Assessment of dosimetry in oncological treatment using radioactive nanoparticles
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Physica Medica - European Journal of Medical Physics
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Introduction: With technological advances in medicine, various
treatments and diagnoses have emerged, contributing to extended
survival for cancer patients. In the ever-evolving landscape of
nanotechnology and medicine, radioactive nanoparticles emerge as
promising agents at the interface of diagnosis and therapy, offering
innovative applications in the field of theranostic medicine capable of
integrating both diagnosis and therapy in a single device. With this
purpose, this study aims to conduct a literature review on the
dosimetry of radioactive nanoparticles, intending to evaluate their
feasibility for oncological treatment.
Materials & Methods: The bibliographic study exclusively focuses on
works related to the dosimetry of radioactive nanoparticles. The
selection involved relevant topics on the Scopus platform (Elsevier),
such as dosimetry, in vivo tests, and preclinical studies involving
radioactive nanoparticles.
Results: Out of 113 selectedworks, 51, 24, and 38 address dosimetry, in
vivo tests, and preclinical studies of radioactive nanoparticles,
respectively. Due to the scarcity of research, all articles were analyzed,
excluding those less cited and less relevant to the objective. Most
studies suggest viability as a treatment, although some do not detail
the dose calculation in the target region.
Summary: This work provides studies on the dosimetry of radioactive
nanoparticles, highlighting a broad distribution of research. While the
treatment shows promising viability, gaps persist, especially in
describing the precise calculation of the dose in the target region,
pointing to opportunities for future research to address this issue.
Como referenciar
RODRIGUES, P.S.; KOKA, A.C. de S.S.; BURIN, A.L.; TALACIMON, C.F.; ROSA, G.M.; MEDEIROS, I.M.M.A.; TEODORO, L.E.H.; ANGELOCI, L.V.; RIGO, M.E.Z.; GESSERAME, M.M.F.; SGRIGNOLI, S.S.; ZEITUNI, C.A.; ROSTELATO, M.E.C.M. Assessment of dosimetry in oncological treatment using radioactive nanoparticles : a comprehensive literature review. Physica Medica, v. 125, p. S498-S499, 2024. Suppl 1. DOI: 10.1016/j.ejmp.2024.104226. Disponível em: https://repositorio.ipen.br/handle/123456789/49745. Acesso em: 27 Apr 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.