A new 124Xe irradiation system for 123I production
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Since 2001, the Nuclear and Energy Research Institute IPEN-CNEN has produced iodine123, weekly, using a manual irradiation system, fully developed in IPEN. Ultrapure 123I has
been produced and distributed to hospitals and clinics, where several diagnostic imaging
procedures are done for thyroid, brain and cardiovascular functions. Due to the short half-life
and emission of low-energy photons, this radioisotope becomes suitable for diagnosis in
children. In the present work, will be presented all the technical and constructive aspects of a
new fully automated irradiation system, dedicated to 123I routine production, employing
enriched xenon-124 gas as the target material. This new system consists of a target, a water
and a helium cooling system, a cryogenic system, an electric power system, and a control and
process monitoring unit, composed of a supervisory software, connected to a programmable
logic controller via personal computer. In this new concept, there is no need for human
interference during radioisotope production, reducing the possibility of eventual failures or
incidents involving radioactive material. In this way, with this new system, a specific yield,
of 2.70 mCi/µAh per irradiation was achieved, in validation essays of the system and, after
three years of routine production of iodine-123, the system showed reliability and resilience.
Como referenciar
COSTA, OSVALDO L. da; BARCELLOS, HENRIQUE; MATSUDA, HYLTON; SUMIYA, LUIZ C. do A.; JUNQUEIRA, FERNANDO de C.; MATSUDA, MARGARETH M. N.; LAPOLLI, ANDRÉ L. A new 124Xe irradiation system for 123I production. SSRN Electronic Journal, p. 1-13, 2023. DOI: 10.2139/ssrn.4434890. Disponível em: https://repositorio.ipen.br/handle/123456789/50076. Acesso em: 02 Jul 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.