MARINA BEATRIZ AGOSTINI VASCONCELLOS

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  • Artigo IPEN-doc 27556
    Information gain in environmental monitoring through bioindication and biomonitoring methods ("B & B technologies") and phytoremediation processes–with special reference to the Biological System of Chemical Elements (BSCE) under specific consideration of Lithium
    2020 - MARKERT, BERND; ABDALLAH, NAGLAA; AKSOY, AHMED; AMMARI, TAREK; ARIAS, ANDRES; AZAIZEH, HASSAN; BADRAN, ADNAN; BALTRĖNAITĖ, EDITA; BAYDOUN, ELIAS; BERNSTEIN, NIRIT; CANHA, NUNO; CHUDZINSKA, EWA; DELAKOWITZ, BERND; DIATTA, JEAN; DJINGOVA, RUMY; EL-SHEIK, OMER; FARGASOVA, AGATA; FIGUEIREDO, ANA M.; FRÄNZLE, STEFAN; FRONTESYEVA, MARINA; GHAFARI, ZAHRA; GOLAN, AVI; GORELOVA, SVETLANA; GREGER, MARIA; HARMENS, HARRY; HILLMAN, JOHN; HOODA, PETER; JAYASEKERA, RANJIT; KIDD, PETRA; KIM, EUN-SHIK; LOPPI, STEFANO; LAHIRI, SUSANTA; LIU, SHIRONG; LUX, ALEXANDER; MA, LENA; MARCOVECCHIO, JORGE; MEERS, ERIK; MENCH, MICHEL; MICHALKE, BERNHARD; MOWAFAQ, MOHAMMED; NAMIESNIK, JACEK; NRIAGU, JEROME; ÖZTÜRK, MUNIR; PACYNA, JOZEF; PEHKONEN, SIMO; RENELLA, GIANCARLO; RINKLEBE, JÖRG; ROBINSON, BRET; SAIKI, MITIKO; SZEFER, PIOTR; TABORS, GUNTIS; TACK, FILIPE; SUCHARA, IVAN; VANGRONSVELD, JACO; VASCONCELLOS, MARINA; WANG, MEIE; WACLAWEK, MARIA; WOLTERBEEK, BERT; WÜNSCHMANN, SIMONE; ZECHMEISTER, HARALD
    Different definitions for the concepts of information, information transfer, i.e. communication and its effect and efficiency of false, but also correct information, especially from the environmental sector, are given. "THE TEN ECOLOGICAL COMMANDMENTS" developed by Menke-Glückert at the end of the 1960s, the 9th commandment "Do not pollute information", in particular, is examined in more detail and understood practically as a currently unchanging law in our existing world societies. The "Ethics Consensus", derived from "THE TEN ECOLOGICAL COMMANDMENTS" and developed by Markert at the end of the 1990s, reflects both theoretical and practical levels of action that many people in our highly diverse world societies can support. From a scientific point of view, this article deals with the so-called B & B technologies, i.e. bioindication and biomonitoring of chemical elements, their chemical speciation as well as organic substances. B & B technologies, which deals with the biological detection of atmospheric deposition of chemical substances on a regional, national, and international level, are taken into account. From both an academic and a practical point of view, mosses have prevailed here in the last decades in addition to lichens. The use of mosses is a major focus of international air monitoring, especially in Europe. Furthermore, the phytoremediation of chemical substances in water, soil and air is described as a biological and sustainable biological process, which does not yet have the full scope as it is used in bioindication and biomonitoring, as shown in the example of mosses. However, the phytoremediation is considered to be an excellent tool to have the leading role in the sustainable pollutant "fight". In the future qualitative and quantitative approaches have been further developed to fit scientifically and practically B&B Technologies as well the different forms of phytotechnological approaches. Finally, the example of lithium, which is optionally derived from the Biological System of Chemical Elements (BSCE), becomes a chemical example that the administration of lithium to ALL mentally conditioned diseases such as manic depression to smoking cigarettes becomes one of the most valuable services for the recovery of human society on a global level. As a conclusion of these tremendous effects of lithium can be considered: pulled out, to make clear that only this chemical element beside a psychiatric care and the involvement of family members, friends, physicians, psychologists and psychiatrists. In addition, it is a must that there is a strong relationship between patient, psychiatrist(s) and strongly related persons to the patient. First an intensive information transfer via communication must be guaranteed. After it, psychological support by doctors and, only if it seems necessary Lithium is to be given in a patient specific dose.
  • Resumo IPEN-doc 27052
    Lysosomal stability in oysters Crassostrea sp. from three different populations from the coast of São Paulo, Brazil
    2017 - CAMARGO, J.; SOUSA, E.P.; CATHARINO, M.G.; GASPARRO, M.R.; ABESSA, D.M.; FERNANDES, I.; LINS, C.G.; VASCONCELLOS, M.B.
    Coastal zones continuously receive inputs of contaminants, which greatly affect its quality. Biological effects resulting from environmental pollution are complex and have not been properly estimated by chemical analysis and toxicity tests. A reliable form to assess the environmental quality consists of analyzing organisms exposed to constant, complex and diffuse sources of contamination. The appropriate use of biomarkers in sentinel organisms may provide an estimate of the potential risk associated with contamination. This study aims to evaluate if different levels of potential contamination affect differently the stress responses in oysters from three sites along the coast of São Paulo state. The physiological condition of oysters Crassostrea sp. from Cananéia (reference site), Santos and Bertioga was studied by analyzing the lysosomal membrane stability in haemocytes, measured using the neutral red retention time (NRRT) assay. Adult organisms were collected in spring (August, September, and October/2016) and autumn (April and May/2017). During the spring, the times of retention of the neutral red dye were similar in oysters from different sites and the reference area (p > 0.05). Interestingly, an uncommon red tide occurred along the coast of the state mainly affecting Cananéia, which may have influenced the reduction of the NRRT for oysters from this region. Such biological events (algal blooms) are more likely to occur at this time of year due to the typical climatic conditions, and may have the potential to even the adverse effects of pollution on distinct bivalve populations subject to different levels of contamination. During the autumn campaign, organisms from both contaminated sites (Santos and Bertioga) showed significant reduction in the mean NRRT relative to the reference site (p < 0.05). A previous study in the same region (Catharino et al., 2015) observed that in both seasons the oysters from Cananéia had a higher NRRT than the oysters from the other two sites. Overall, the NRRT were lower in the present study. These results may be due to the exposure of the organisms to pollutants, since lysosomes are organelles that absorb a wide variety of organic and inorganic substances. However, further investigations are required and being carried out to confirm this hypothesis.
  • Livro IPEN-doc 26714
    O IPEN e a saúde
    2019 - LINARDI, MARCELO; NETTO, ANA P.F.A.; LUGAO, ADEMAR B.; FREITAS, ANDERSON Z. de; CARBONARI, ARTUR W.; ZEITUNI, CARLOS A.; SOARES, CARLOS R.J.; SILVA, CECILIA C.G. e; ZAMBONI, CIBELE B.; PERONI, CIBELE N.; VIEIRA, DANIEL P.; ANDRADE, DELVONEI A. de; ZEZELL, DENISE M.; LAZAR, DOLORES R.R.; PARRA, DUCLERC F.; MOREIRA, EDSON G.; LANDULFO, EDUARDO; FONSECA, EDVALDO R.P. da; PERINI, EFRAIN A.; ARAUJO, ELAINE B. de; MUCCILLO, ELIANA N. dos S.; CARVALHO, ELITA F.U. de; BERNARDES, EMERSON S.; MOURA, ESPERIDIANA A.B. de; SILVA, FABIANA M. da; MOREIRA, FERNANDO J.F.; SILVA, FLAVIA R. de O.; GENEZINI, FREDERICO A.; ALVES, GLAUCIE J.; YORIYAZ, HELIO; COSTA, ISOLDA; MENGATTI, JAIR; ROSSI, JESUALDO L.; OLIVEIRA, JOAO E. de; SARKIS, JORGE E. de S.; PERROTTA, JOSE A.; ROGERO, JOSE R.; SHORTO, JULIAN M.B.; SILVA, LEONARDO G. de A. e; MOLNARY, LESLIE de; RODRIGUES, LETICIA L.C.; DIAS, LIGIA E.M.F.; CALDAS, LINDA V.E.; POZZO, LORENA; GENOVA, LUIS A.; MATSUDA, MARGARETH M.N.; HAMADA, MARGARIDA M.; FELINTO, MARIA C.F. da C.; POTIENS, MARIA da P.A.; ROSTELATO, MARIA E.C.M.; MARUMO, MARIA H.B.; VASCONCELLOS, MARINA B.A.; RIBEIRO, MARTHA S.; COTRIM, MARYCEL E.B.; NEVES, MAURICIO D.M. das; MORALLES, MAURICIO; DIAS, MAURO da S.; IGAMI, MERY P.Z.; DURAZZO, MICHELANGELO; SUZUKI, MIRIAM F.; SAIKI, MITIKO; MATHOR, MONICA B.; VIEIRA JUNIOR, NILSON D.; BARTOLINI, PAOLO; SPENCER, PATRICK J.; SILVA, PAULO S.C. da; AFFONSO, REGINA; CARNEIRO, REGINA C.G.; ROGERO, SIZUE O.; SAKATA, SOLANGE K.; CASTANHO, SONIA R.H. de M.; MAIHARA, VERA A.; ROSSI, WAGNER de; CALVO, WILSON A.P.; KODAMA, YASKO
  • Resumo IPEN-doc 25935
    Radionuclides of natural origin in a Brazilian mussel reference material
    2018 - MOREIRA, E.G.; VASCONCELLOS, M.B.A.; ROSA, M.M.L.; TADDEI, M.H.T.
    Certified reference materials are important tools for the quality assurance of analytical results. However there are several constraints for their widespread use in developing countries such as lack of technological development or difficult access to imported goods. Another issue is that analyte level differences between imported certified reference materials and local laboratory samples may be a concern in the measurement process. This contribution presents the activity concentrations of 234U, 235U, 238U and 232Th determined by alpha spectrometry after a radiochemical separation procedure and 40K and 210Pb determined by gamma-ray spectrometry in a Perna perna mussel reference material produced in Brazil. The activity concentrations obtained were included as information values in the certification process of the reference material.
  • Artigo IPEN-doc 25791
    Micro-homogeneity evaluation of a bovine kidney candidate reference material
    2019 - CASTRO, L.; MOREIRA, E.G.; VASCONCELLOS, M.B.A.
    The minimum sample intake for which a reference material remains homogeneous is one of the parameters that must be estimated in the homogeneity assessment study of reference materials. In this work, Instrumental Neutron Activation Analysis was used to evaluate this quantity in a bovine kidney candidate reference material. The mass fractions of 9 inorganic constituents were determined in subsamples between 1 and 2 mg in order to estimate the relative homogeneity factor (HE) and the minimum sample mass to achieve 5% and 10% precision on a 95% confidence level. Results ob-tained for HE in all the analyzed elements were satisfactory. The estimated minimum sample intake was between 2 mg and 40 mg, depending on the element.
  • Artigo IPEN-doc 25077
    Stability assessment of a bovine kidney reference-material candidate
    2018 - CASTRO, LILIANA; MOREIRA, EDSON G.; VASCONCELLOS, MARINA B.A.; LANGE, CAMILA N.; PEDRON, TATIANA; BATISTA, BRUNO L.
    Reference materials are used worldwide and necessary for quality control purposes during analytical determinations. The present study describes the stability evaluation of a bovine kidney reference-material candidate. An isochronous layout was performed, in which the flasks involved are exposed at different temperatures for different time periods and then are analyzed at the same time at the end of the study. The mass fractions of ten inorganic constituents were determined using instrumental neutron activation analysis and inductively coupled plasma mass spectrometry. Statistical analysis, univariate and multivariate, showed no significant differences in composition between units exposed to the different temperatures and times. The reference material may be transported under normal transportation conditions and the certified values and uncertainties will continue to be valid for a period of 2 years.
  • Artigo IPEN-doc 24355
    Interlaboratory comparison for the characterization of a brazilian mussel reference material
    2018 - MOREIRA, EDSON G.; VASCONCELLOS, MARINA B.A.; MAIHARA, VERA A.; CATHARINO, MARILIA G.M.; SAIKI, MITIKO
    Bivalve mollusks have long been used in biomonitoring studies to assess seawater environmental status. The use of suitable certified reference materials is a straightforward means to attain quality assurance in such studies as they allow the traceability of measurement results, making it possible the comparison of data obtained at different places and periods of time. This paper describes the certification of element mass fractions for a Perna perna mussel reference material produced in Brazil. After homogeneity and stability studies, an interlaboratory comparison was performed for element characterization. Robust means were taken as assigned values and contributions due to element characterization and from homogeneity and stability studies were taken into account to yield expanded uncertainties. From the adopted certification criteria, informative values for 20 elements were obtained and it was possible to assign certified values for the following 16 elements: Al, As, Ca, Cd, Cl, Co, Cu, Fe, K, Mg, Mn, Na, Ni, Se, Th and Zn.
  • Resumo IPEN-doc 24559
    Evaluation of mercury levels in hair of children residents in garimpo area on the city of Chapada de Natividade – Tocantins
    2017 - VASCONCELLOS, M.B.A.; MENDES, S.U.R.; CATHARINO, M.G.M.; QUINAGLIA, G.A.; HELD, B.
    The objective of the work is to evaluate the mercury exposure of children living in the artisanal gold mining are and in a control area, without mining. A cross-sectional study was conducted with children living in the municipalities of Chapada de Natividade and Porto Nacional, in the State of Tocantins, where hair samples were collected for laboratorial analysis of mercury concentrations, comparing between municipalities, gender, monthly fish consumption, profession of parents and the presence of amalgam in dental restorations. The participating children were selected from informations registered in the cadaster of the service of basic health assistance of Brazil (SUS).The age range chosen was of children from 5 to 6 years, with the aim of not including older children, which might be already submitted to work in the artisanal gold mining activities. The hair samples were analyzed by the methods of neutron activation analysis and also by means of the DMA (Direct Mercury Analyzer) equipment, in the last case being a partnership with CETESB. There was no evidence of mercury-related diseases in the studied children. The mean concentration of mercury in children in Chapada de Natividade was significantly higher than in Porto Nacional. Children exposed to artisanal gold mining areas have higher concentrations of mercury than children living in non- artisanal gold mining areas. There was no significant relationship between mercury concentrations and gender, monthly fish consumption, parental profession and amalgam presence in dental restorations.
  • Resumo IPEN-doc 24552
    Micro-homogeneity evaluation of a bovine kidney candidate reference material
    2017 - CASTRO, L.; MOREIRA, E.G.; VASCONCELLOS, M.B.A.
    Assessing the homogeneity is one of the critical steps in the process of preparing and certifying a reference material (RM). One of the parameters that must be estimated is the minimum sample intake for which the material remains homogeneous, that is, that the concentration and uncertainty values present in the certificate continue to be valid. In general, the Certified Reference Materials (CRM) producers establish a minimum sample intake of 200mg, estimated in a conservative way, and useful for classical analytical methods that use sample masses greater than this value. From the appearance of analytical techniques that use less sample quantities, such as ICP, it became increasingly important to be able to clearly estimate which is the real minimum sample intake of the RM. The present work describes the micro-homogeneity study of a bovine kidney candidate reference material. In order to obtain an estimate of the minimum sample intake amount, assays were performed to determine the Kurfurst constant (HE), a parameter used for this purpose by several authors. Measurements should be carried out using a method that allows analyzing a low sample quantity, with good accuracy and low uncertainty. In this work was used Instrumental Neutron Activation Analysis, INAA, a reference technique for the evaluation of the degree of homogeneity of RM. Ten sub-samples of approximately 1mg were analyzed to evaluate the HE for the elements Cl, K, Mn and Na, and ten sub-samples of approximately 2mg to evaluate the HE for Co, Fe, Mg, Se and Zn. Results obtained for HE in all the analyzed elements were satisfactory. The estimated minimum sample intake was between 1mg and 50mg, depending of the element.
  • Resumo IPEN-doc 24542
    Preparation of biological reference materials at LAN – IPEN – CNEN/SP
    2017 - MOREIRA, E.G.; MAIHARA, V.A.; CASTRO, L.; VASCONCELLOS, M.B.A.
    Three biological reference materials were prepared to be used in interlaboratory programs and/or proficiency tests, as well as, for calibration of analytical instruments and validation of analytical methods for environmental trace elements: A Perna perna mussel reference material was produced and certified by means of an interlaboratory comparison. The material was designed as a quality assurance tool for element biomonitoring studies along the Brazilian seashore. For the preparation of the Brazilian mussel reference material, 164kg of Perna perna (Linnaeus, 1758) mussels were purchased from a single producer, from Cocanha Beach in Caraguatatuba City, São Paulo State North Shore where mussels are cultivated by the longline system. After cleaning, freeze-drying and homogenization, the mussel samples were packed in 171 bottles and, the material was irradiated with a gamma ray dose of 5 kGy to enhance its stability. The certified mass fraction values and associated expanded uncertainties were obtained for Al, As, Ca, Cd, Cl, Co, Cu, Fe, K, Mg, Mn, Na, Ni, Se, Th and Zn at the certification campaign. A fish tissue reference material was produced in the context of an International Atomic Energy Agency (IAEA) project aiming analytical quality improvement for laboratories of the Latin American and Caribbean region. Whitemouth croake (Micropogonias furnieri), known as corvina, was the chosen species due to its low cost and high consumption in Latin America countries. For preparation, about 300kg of fish was collected and only the edible parts were used. After adequate processing, the fish material was bottled in 534 bottles with approximately 25g each. The reference values and associated expanded uncertainty (k = 2) were established for As, Cd, Cu, Fe, K, Mn, Na, Se and Zn; Finally, a bovine kidney reference material to be used in the quality control of meat products was prepared using 35 kg of fresh bovine kidney from cattle reared under controlled feeding conditions. The preparation resulted in a final batch of 175 flasks. It was possible to assign values to 20 elements with their respective uncertainties, being 9 certified values (As, Cu, Fe, K, Mg, Mn, Na, Se and Zn), 10 indicative values (Br, Ca, Cd, Cl, Co, Cs, Hf, Mo, P and Rb) and 1 as additional information (Hg). All the three reference material production projects took advantage of the unique metrological properties of Instrumental Activation Analysis (INAA) not only in the certification process but also in the homogeneity and stability assessment following ISO Guide 30 series recommendations.