RENATO ARAÚJO PRATES
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Artigo IPEN-doc 23119 Low Intensity laser therapy in patients with burning mouth syndrome: a randomized, placebo-controlled study2016 - SUGAYA, NORBERTO N.; SILVA, ERICA F.P. da; KATO, ILKA T.; PRATES, RENATO; GALLO, CAMILA de B.; PELLEGRINI, VIVIAN D.The aim of this study was to assess the effectiveness of low intensity laser therapy in patients with Burning Mouth Syndrome (BMS). Thirty BMS subjects were randomized into two groups -Laser (LG) and Placebo (CG). Seven patients dropped out, leaving 13 patients in LG and 10 patients in CG. Each patient received 4 irradiations (laser or placebo) twice a week, for two consecutive weeks (blinded to the type of irradiation received). Infrared laser (AsGaAI) irradiations were applied to the affected mucosa in scanning mode, wavelength of 790 nm, output power of 20 mW and fluence of 6 J/cm(2). A visual analogue scale (VAS) was used to assess the therapeutic effect before and after each irradiation, and at all the control time periods: 7, 14, 30, 60 and 90 days after the last irradiation. One researcher delivered irradiation and another recorded the results. Both researchers were blinded, the first to the results, and the second to the type of radiation applied. The results were categorized according to the percentage of symptom level variation, and showed a statistically better response in LG in only two categories of the control checkpoints (p=0.02; Fisher's Exact Test). According to the protocol used in this study, low intensity laser therapy is as beneficial to patients with BMS as placebo treatment, indicating a great emotional component of involvement in BMS symptomatology. Nevertheless, there were positive results in some statistical analyses, thus encouraging further research in BMS laser therapy with other irradiation parameters.Resumo IPEN-doc 13825 Infrared laser irradiation applied to the treatment of burning mouth syndrome2008 - KATO, ILKA T.; PELLEGRINI, VIVIAN; PRATES, RENATO A.; WETTER, NIKLAUS U.; RIBEIRO, MARTHA S.; SUGAYA, NORBERTO N.Resumo IPEN-doc 18928 Low intensity laser therapy in burning mouth syndrome: clinical trial2012 - PELLEGRINI, V.D.; FREO, B.; PATRICIO, E.F.; PRATES, R.A.; KATO, I.T.; LEMOS JUNIOR, C.A.; SUGAYA, N.N.Artigo IPEN-doc 15661 Terapia com laser em baixa intensidade no tratamento da síndrome de ardência bucal2010 - KATO, ILKA T.; PELLEGRINI, VIVIAN D.; PRATES, RENATO A.; RIBEIRO, MARTHA S.; SUGAYA, NORBERTO N.O objetivo do presente estudo foi relatar os efeitos da terapia com Laser em baixa intensidade na sintomatologia de dois pacientes portadores da síndrome de ardência bucal. Foram atendidas duas pacientes do sexo feminino, com idade de 69 e 52 anos e histórico de 2 e 4 anos de doença. Após a realização de exames físico e laboratoriais para confirmar o diagnóstico da doença, os pacientes foram tratados com Laser de diodo, com emissão em 790 nm, 120 mW e 6 J/cm2, uma vez por semana, por três semanas. A intensidade de ardência foi mensurada por meio da escala visual analógica (VAS) no início do estudo, após cada sessão de terapia com Laser, 7 e 42 dias após o término do tratamento. Os pacientes foram solicitados a fazer uma avaliação diária do sintoma utilizando uma escala numérica de 0 a 10. De forma geral, os pacientes apresentaram diminuição gradual da ardência após o início do tratamento. Ao término das três sessões de irradiação observou-se redução do sintoma de 56% a 95%. Dois sítios de uma paciente apresentaram retomo parcial na intensidade de ardência após o término do tratamento. Com base nos resultados obtidos, a terapia com Laser em baixa intensidade pode ser apontada como uma futura alternativa para tratamento dos pacientes acometidos pela SAB.Artigo IPEN-doc 16109 Low-level laser therapy in burning mouth syndrome patients2010 - KATO, ILKA T.; PELLEGRINI, VIVIAN D.; PRATES, RENATO A.; RIBEIRO, MARTHA S.; WETTER, NIKLAUS U.; SUGAYA, NORBERTO N.Objective: The aim of this study was to investigate the effect of low-level laser therapy (LLLT) on the treatment of burning mouth syndrome (BMS). In addition, the laser effect was compared on the different affected oral sites. Materials and Methods: Eleven subjects with a total of 25 sites (tongue, lower lip, upper lip, and palate) affected by a burning sensation were selected. The affected areas were irradiated once a week for three consecutive weeks with an infrared laser (l ¼ 790 nm). The probe was kept in contact with the tissue, and the mucosal surface was scanned during the irradiation. The exposure time was calculated based on the fluence of 6 J/cm2 , the output power of 120 mW, and the area to be treated. Burning intensity was recorded through a visual analog scale before and after the treatment and at the 6-week follow-up. The percentage of the improvement in symptoms was also obtained. Results: Burning intensity at the end of the laser therapy was statistically lower than at the beginning ( p < 0.01). Patients reported an 80.4% reduction in the intensity of symptoms after laser treatment. There was no statistical difference between the end of the treatment and the 6-week follow-up, except for the tongue site. Conclusion: Under the investigated parameters, infrared LLLT proved to be a valuable alternative for BMS treatment, providing a significant and lasting reduction in symptoms.