In vitro assessment of the composition and microhardness of the hard tissues of oral cavity submitted to gamma irradiation

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dc.contributor.authorPAREDES, WILBER E.B.
dc.contributor.authorARI, SANDRA F.
dc.contributor.authorGERALDO, AUREA B.C.
dc.contributor.authorANDRADE, DELVONEI A. de
dc.coverageInternacionalpt_BR
dc.date.accessioned2017-09-28T12:37:39Z
dc.date.available2017-09-28T12:37:39Z
dc.date.issued2017pt_BR
dc.description.abstractIntroduction: Clinical radiotherapy is one of the most important techniques for the treatment of malignant lesions in head and neck; however, exposure to ionizing radiation may lead to both systemic and local complications, immediately and after this treatment, where the main issue is the xerostomia and its consequent oral mucositis. Regarding late complications produced by radiation, decay of radiation and osteoradionecrosis, both dosedependent lesions, showed a high level of incidence in recent decades and it would be difficult to manage, although patients referred after treatment’s completion and under the influence of local factors. Methodology: Then, This study evaluated the effect of ionizing radiation from gamma source onto samples of enamel, root dentin and jawbone samples undergone to the same absorbed dose / dose rate that those in patients with head and neck cancer. The non-irradiated and irradiated samples were analyzed by microhardness surface analysis; scanning electron microscopy (SEM) and Fourier transform infrared spectrometry (FTIR). Results and discussion: Microhardness data were analyzed statistically with a confidence level of 95% (p value <0.05%), using parametric Student’s t-test for related averages and ANOVA statistical test, finding a statistically significant result (p = 0.00) to all four groups samples. Conclusion: It was observed a high deleterious and statistical significant effect of gamma radiation on hard tissues from oral cavity, regarding to physical, compositional and morphological properties.pt_BR
dc.format.extent1-12pt_BR
dc.identifier.citationPAREDES, WILBER E.B.; ARI, SANDRA F.; GERALDO, AUREA B.C.; ANDRADE, DELVONEI A. de. In vitro assessment of the composition and microhardness of the hard tissues of oral cavity submitted to gamma irradiation. <b>International Journal of Cancer Research & Therapy</b>, v. 2, n. 1, p. 1-12, 2017. Disponível em: http://repositorio.ipen.br/handle/123456789/27812.
dc.identifier.fasciculo1pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6689-3011
dc.identifier.percentilfiSem Percentilen
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/27812
dc.identifier.vol2pt_BR
dc.relation.ispartofInternational Journal of Cancer Research & Therapypt_BR
dc.rightsopenAccesspt_BR
dc.subjectanimal tissues
dc.subjectgamma radiation
dc.subjecthead
dc.subjectradiation doses
dc.subjectscanning electron microscopy
dc.subjectin vitro
dc.subjectinfrared spectra
dc.subjectirradiation
dc.subjectmicrohardness
dc.subjectmucous membranes
dc.subjectneck
dc.subjectoral cavity
dc.subjectradiation effects
dc.subjectradiotherapy
dc.subjecttesting
dc.titleIn vitro assessment of the composition and microhardness of the hard tissues of oral cavity submitted to gamma irradiationpt_BR
dc.typeArtigo de periódicopt_BR
dspace.entity.typePublication
ipen.autorDELVONEI ALVES DE ANDRADE
ipen.autorAUREA BEATRIZ CERQUEIRA GERALDO
ipen.autorWILBER EDISON BERNAOLA PAREDES
ipen.codigoautor1258
ipen.codigoautor1466
ipen.codigoautor12706
ipen.contributor.ipenauthorDELVONEI ALVES DE ANDRADE
ipen.contributor.ipenauthorAUREA BEATRIZ CERQUEIRA GERALDO
ipen.contributor.ipenauthorWILBER EDISON BERNAOLA PAREDES
ipen.date.recebimento17-09pt_BR
ipen.identifier.fiSem F.I.pt_BR
ipen.identifier.ipendoc23123pt_BR
ipen.type.genreArtigo
relation.isAuthorOfPublication0eeb4436-68e5-4573-a603-35f5fc912178
relation.isAuthorOfPublication825a6fc8-dbf1-471f-aeba-bedec4f0f7a3
relation.isAuthorOfPublication9b5f9837-2642-4d15-8feb-5631fab967fd
relation.isAuthorOfPublication.latestForDiscovery9b5f9837-2642-4d15-8feb-5631fab967fd
sigepi.autor.atividadePAREDES, WILBER E.B.:12706:920:Spt_BR
sigepi.autor.atividadeGERALDO, AUREA B.C.:1466:220:Npt_BR
sigepi.autor.atividadeANDRADE, DELVONEI A. DE:1258:420:Npt_BR
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