A dosimetric evaluation using the Monte Carlo method considering geometric variations of the Iodine-125 seed for brachytherapy
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Brazilian Journal of Radiation Sciences
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Resumo
The Institute for Energy and Nuclear Research – IPEN-CNEN/SP is uniquely
positioned to develop a new source of Iodine-125 for brachytherapy treatment.
Therefore, research into the dosimetric process and source design is widely studied. Task
Group 43 – TG 43 cites methodologies for dosimetry of sources for brachytherapy, the
most used method is Monte Carlo. However, the dosimetric protocol does not mention
possible variations in the source geometry after its conception. The investigative focus of
the work was to obtain measurements of the Iodine-125 seed during the production stages
until completion, quantify them and simulate them using the Monte Carlo method with
the MCNP – 4C code, the formalism was in water and a 101x101 matrix was used to
calculate the dose point by point. Two variations were chosen: a) seed length; b) nucleus
length, using a batch of 100 seeds for each case. 100 simulations were carried out for each
variation and one simulation using the reference seed geometry. The following
calculations were applied: relative difference to compare variations to the reference;
average among the 100 seeds of each batch to calculate the standard deviation. In both
cases there was no point that exceeded 4.48% relative difference, and for standard
deviation the largest point was 1.6%, while the Type A uncertainty was 0.018% at the
largest point.
Como referenciar
CHICO, H.S.; ANGELOCCI, L.V.; ZEITUNI, C.A.; SOUZA, C.D.; SGRIGNOLI, S.S.; ROSTELATO, M.E.C.M. A dosimetric evaluation using the Monte Carlo method considering geometric variations of the Iodine-125 seed for brachytherapy. Brazilian Journal of Radiation Sciences, v. 12, n. 4A, p. 1-21, 2024. DOI: 10.15392/2319-0612.2024.2543. Disponível em: https://repositorio.ipen.br/handle/123456789/49079. Acesso em: 20 Jan 2026.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.