Comparison between gold nanoparticles synthesized by radiolysis and by EGCG-driven gold reduction

Página do item simplificado
dc.contributor.authorFREITAS, LUCAS F. dept_BR
dc.contributor.authorCRUZ, CASSIA P.C. dapt_BR
dc.contributor.authorCAVALCANTE, ADRIANA K.pt_BR
dc.contributor.authorBATISTA, JORGE G. dos S.pt_BR
dc.contributor.authorVARCA, GUSTAVO H.C.pt_BR
dc.contributor.authorMATHOR, MONICA B.pt_BR
dc.contributor.authorLUGAO, ADEMAR B.pt_BR
dc.coverageInternacionalpt_BR
dc.date.accessioned2020-10-13T17:39:29Z
dc.date.available2020-10-13T17:39:29Z
dc.date.issued2020pt_BR
dc.description.abstractRadiolytic synthesis and phytochemical-driven gold reduction for the generation of nanoparticles are successful examples of Green Chemistry applied for nanomaterials. The present work compares these two green approaches focusing on hydrodynamic size, stability over time, optical properties and toxicity in NIH 3T3 (ATCC® CRL- 1658™) cells and Danio rerio (Zebra Fish). The radiolytic synthesis was performed by mixing 1 mM NaAuCl4; polyvinyl pyrrolidone 0.5%, AgNO3 6×10−5 M, propan-2-ol 0.2 M and acetone 0.06 M, followed by irradiation at 15 kGy (5 kGy h−1, 60Co source). The EGCG-functionalized nanoparticles were synthesized by mixing 1.6 mM of Au with 0.8 mM of EGCG in phosphate buffer (10 mM) for 2 h. Both methods yield the formation of gold nanoparticles featuring plasmon resonance bands at 520–530 nm, polydispersity above 0.3 was relevant only for the radiolytic protocol. Regarding stability over time, after 30 days, the nanoparticles synthesized radiolytically presented no relevant size changes, while some aggregation was observed for the EGCG-particles. The same nanoparticles demonstrated a lack of stability in high ionic strength medium. Slight toxicity was observed for the EGCG-nanoparticles in Danio rerio, with an IC50 calculated as 40.49%, while no IC50 was established within the concentration range of radiolysis-AuNPs used in this study. In conclusion, both green methods generated nanoparticles with good control of size and optical properties, especially via reduction by EGCG. However, the stability and toxicity results were found to be more promising for the radiolytically synthesized gold nanoparticles.pt_BR
dc.description.sponsorshipInternational Atomic Energy Agency (IAEA)pt_BR
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)pt_BR
dc.description.sponsorshipIDIAEA: CRP F22064pt_BR
dc.description.sponsorshipIDCNPq: 402887/2013-1pt_BR
dc.format.extent1-9pt_BR
dc.identifier.citationFREITAS, LUCAS F. de; CRUZ, CASSIA P.C. da; CAVALCANTE, ADRIANA K.; BATISTA, JORGE G. dos S.; VARCA, GUSTAVO H.C.; MATHOR, MONICA B.; LUGAO, ADEMAR B. Comparison between gold nanoparticles synthesized by radiolysis and by EGCG-driven gold reduction. <b>Radiation Physics and Chemistry</b>, v. 174, p. 1-9, 2020. DOI: <a href="https://dx.doi.org/10.1016/j.radphyschem.2020.108959">10.1016/j.radphyschem.2020.108959</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/31427.
dc.identifier.doi10.1016/j.radphyschem.2020.108959pt_BR
dc.identifier.issn0969-806Xpt_BR
dc.identifier.orcid0000-0002-1737-3191pt_BR
dc.identifier.orcid0000-0002-7294-9106pt_BR
dc.identifier.orcid0000-0002-6545-237Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1737-3191
dc.identifier.orcidhttp://orcid.org/0000-0002-7294-9106
dc.identifier.percentilfi66.43pt_BR
dc.identifier.percentilfiCiteScore72.00
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/31427
dc.identifier.vol174pt_BR
dc.relation.ispartofRadiation Physics and Chemistrypt_BR
dc.rightsopenAccesspt_BR
dc.sourceInternational Meeting on Radiation Processing, 19th, April 01-05, 2019, Strasbourg, Francept_BR
dc.subjectgold
dc.subjectnanoparticles
dc.subjectsynthesis
dc.subjectchemistry
dc.subjectecology
dc.subjectpolyphenols
dc.subjectfishes
dc.titleComparison between gold nanoparticles synthesized by radiolysis and by EGCG-driven gold reductionpt_BR
dc.typeArtigo de periódicopt_BR
dspace.entity.typePublication
ipen.autorADRIANA KUCHINSKI CAVALCANTE
ipen.autorJORGE GABRIEL DOS SANTOS BATISTA
ipen.autorADEMAR BENEVOLO LUGAO
ipen.autorMONICA BEATRIZ MATHOR
ipen.autorGUSTAVO HENRIQUE COSTAVARCA
ipen.autorCASSIA PRISCILA CUNHA DA CRUZ
ipen.autorLUCAS FREITAS DE FREITAS
ipen.codigoautor12073
ipen.codigoautor10274
ipen.codigoautor339
ipen.codigoautor209
ipen.codigoautor8661
ipen.codigoautor15070
ipen.codigoautor14818
ipen.contributor.ipenauthorADRIANA KUCHINSKI CAVALCANTE
ipen.contributor.ipenauthorJORGE GABRIEL DOS SANTOS BATISTA
ipen.contributor.ipenauthorADEMAR BENEVOLO LUGAO
ipen.contributor.ipenauthorMONICA BEATRIZ MATHOR
ipen.contributor.ipenauthorGUSTAVO HENRIQUE COSTAVARCA
ipen.contributor.ipenauthorCASSIA PRISCILA CUNHA DA CRUZ
ipen.contributor.ipenauthorLUCAS FREITAS DE FREITAS
ipen.date.recebimento20-10
ipen.identifier.fi2.858pt_BR
ipen.identifier.fiCiteScore3.8
ipen.identifier.ipendoc27201pt_BR
ipen.identifier.iwosWoSpt_BR
ipen.range.fi1.500 - 2.999
ipen.range.percentilfi50.00 - 74.99
ipen.type.genreArtigo
relation.isAuthorOfPublicationb0ca3d5f-34ef-4296-a9ef-afb8e9886957
relation.isAuthorOfPublicationd71d578f-dbbd-4ff9-adf8-929b13d23037
relation.isAuthorOfPublication99ac24c5-2ae1-465a-a6f2-40b4d9af6af7
relation.isAuthorOfPublication742b424f-9dfb-4e4a-993b-000052bb1313
relation.isAuthorOfPublication46f998cf-b207-4854-94c0-dd2def4eec2a
relation.isAuthorOfPublication296b0b7e-28f4-4658-b7d4-f52e0494fe8f
relation.isAuthorOfPublication05be75ae-89a2-47f4-a13a-7723b50a6bd0
relation.isAuthorOfPublication.latestForDiscovery05be75ae-89a2-47f4-a13a-7723b50a6bd0
sigepi.autor.atividadeLUGAO, ADEMAR B.:339:740:Npt_BR
sigepi.autor.atividadeMATHOR, MONICA B.:209:220:Npt_BR
sigepi.autor.atividadeVARCA, GUSTAVO H.C.:8661:740:Npt_BR
sigepi.autor.atividadeBATISTA, JORGE G. dos S.:10274:740:Npt_BR
sigepi.autor.atividadeCAVALCANTE, ADRIANA K.:12073:740:Npt_BR
sigepi.autor.atividadeFREITAS, LUCAS F. de:14818:740:Spt_BR
sigepi.autor.atividadeCRUZ, CASSIA P.C. da:15070:740:N
Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
27201.pdf
Tamanho:
2.2 MB
Formato:
Adobe Portable Document Format
Descrição:
Baixar
Licença do Pacote
Agora exibindo 1 - 1 de 1
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Baixar
Coleções
Periódicos