A novel bone scaffolds based on hyperbranched polyglycerol fibers filled with hydroxyapatite nanoparticles: in vitro cell response
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Key Engineering Materials
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A novel bone scaffolding material was successfully fabricated by electrospinning from hyperbranched polyglycerol (HPGL) solutions containing nanoparticles of hydroxyapatite (HA). The potential use of the electrospun fibrous HPGL-HA scaffolds for bone regeneration was evaluated in vitro with human osteoblasts in terms of alkaline phosphatase (ALP) activity of the cells that were cultured directly on the scaffolds. The results were compared with those on corresponding HPLG-HA solution-cast film scaffolds. It was found that all of the fibrous scaffolds promoted much better adhesion and proliferation of cells than the corresponding film scaffolds.
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QUEIROZ, ALVARO A.A. de; BRESSIANI, JOSE C.; BRESSIANI, ANA H.; HIGA, OLGA Z.; ABRAHAM, GUSTAVO A. A novel bone scaffolds based on hyperbranched polyglycerol fibers filled with hydroxyapatite nanoparticles: in vitro cell response. Key Engineering Materials, v. 396-398, p. 633-636, 2009. DOI: 10.4028/www.scientific.net/KEM.396-398.633. Disponível em: http://repositorio.ipen.br/handle/123456789/4876. Acesso em: 30 Dec 2025.
Esta referência é gerada automaticamente de acordo com as normas do estilo IPEN/SP (ABNT NBR 6023) e recomenda-se uma verificação final e ajustes caso necessário.