A novel bone scaffolds based on hyperbranched polyglycerol fibers filled with hydroxyapatite nanoparticles: in vitro cell response

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dc.contributor.authorQUEIROZ, ALVARO A.A. dept_BR
dc.contributor.authorBRESSIANI, JOSE C.pt_BR
dc.contributor.authorBRESSIANI, ANA H.pt_BR
dc.contributor.authorHIGA, OLGA Z.pt_BR
dc.contributor.authorABRAHAM, GUSTAVO A.pt_BR
dc.coverageInternacionalpt_BR
dc.date.accessioned2014-07-15T13:41:48Zpt_BR
dc.date.accessioned2014-07-30T11:51:06Z
dc.date.available2014-07-15T13:41:48Zpt_BR
dc.date.available2014-07-30T11:51:06Z
dc.date.issued2009pt_BR
dc.description.abstractA novel bone scaffolding material was successfully fabricated by electrospinning from hyperbranched polyglycerol (HPGL) solutions containing nanoparticles of hydroxyapatite (HA). The potential use of the electrospun fibrous HPGL-HA scaffolds for bone regeneration was evaluated in vitro with human osteoblasts in terms of alkaline phosphatase (ALP) activity of the cells that were cultured directly on the scaffolds. The results were compared with those on corresponding HPLG-HA solution-cast film scaffolds. It was found that all of the fibrous scaffolds promoted much better adhesion and proliferation of cells than the corresponding film scaffolds.
dc.format.extent633-636pt_BR
dc.identifier.citationQUEIROZ, ALVARO A.A. de; BRESSIANI, JOSE C.; BRESSIANI, ANA H.; HIGA, OLGA Z.; ABRAHAM, GUSTAVO A. A novel bone scaffolds based on hyperbranched polyglycerol fibers filled with hydroxyapatite nanoparticles: in vitro cell response. <b>Key Engineering Materials</b>, v. 396-398, p. 633-636, 2009. DOI: <a href="https://dx.doi.org/10.4028/www.scientific.net/KEM.396-398.633">10.4028/www.scientific.net/KEM.396-398.633</a>. Disponível em: http://repositorio.ipen.br/handle/123456789/4876.
dc.identifier.doi10.4028/www.scientific.net/KEM.396-398.633
dc.identifier.issn1013-9826pt_BR
dc.identifier.urihttp://repositorio.ipen.br/handle/123456789/4876pt_BR
dc.identifier.vol396-398pt_BR
dc.relation.ispartofKey Engineering Materialspt_BR
dc.rightsopenAccessen
dc.sourceApresentado tambem em: International Symposium on Ceramics in Medicine, 21st, Buzios, RJ, 21-24 october, 2008pt_BR
dc.subjectbone tissuespt_BR
dc.subjectglycerolpt_BR
dc.subjectapatitespt_BR
dc.subjectnanostructurespt_BR
dc.subjectin vitropt_BR
dc.subjectbiological regenerationpt_BR
dc.subjectconnective tissue cellspt_BR
dc.titleA novel bone scaffolds based on hyperbranched polyglycerol fibers filled with hydroxyapatite nanoparticles: in vitro cell responsept_BR
dc.typeArtigo de periódicopt_BR
dspace.entity.typePublication
ipen.autorOLGA ZAZUCO HIGA
ipen.autorANA HELENA DE ALMEIDA BRESSIANI
ipen.autorJOSE CARLOS BRESSIANI
ipen.codigoautor1023
ipen.codigoautor96
ipen.codigoautor1459
ipen.contributor.ipenauthorOLGA ZAZUCO HIGA
ipen.contributor.ipenauthorANA HELENA DE ALMEIDA BRESSIANI
ipen.contributor.ipenauthorJOSE CARLOS BRESSIANI
ipen.date.recebimento09-10pt_BR
ipen.identifier.fiSem F.I.pt_BR
ipen.identifier.ipendoc14077pt_BR
ipen.identifier.iwosWoSpt_BR
ipen.type.genreArtigo
relation.isAuthorOfPublicationeeaeef03-7bd8-4788-ba3d-5c02800475bd
relation.isAuthorOfPublication04d834e7-faee-4461-8fa7-5e5071ec48cc
relation.isAuthorOfPublicationf9cbec71-8864-4175-998d-637777f90c2d
relation.isAuthorOfPublication.latestForDiscoveryf9cbec71-8864-4175-998d-637777f90c2d
sigepi.autor.atividadeBRESSIANI, JOSE C.:1459:720:Npt_BR
sigepi.autor.atividadeBRESSIANI, ANA H.:96:720:Npt_BR
sigepi.autor.atividadeHIGA, OLGA Z.:1023:820:Npt_BR

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